Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult
Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2012/473790 |
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| author | Toshihide Takahashi Eiichi Ishikawa Yosuke Masuda Tetsuya Yamamoto Taiki Sato Makoto Shibuya Akira Matsumura |
| author_facet | Toshihide Takahashi Eiichi Ishikawa Yosuke Masuda Tetsuya Yamamoto Taiki Sato Makoto Shibuya Akira Matsumura |
| author_sort | Toshihide Takahashi |
| collection | DOAJ |
| description | Intracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an enhanced mass lesion with a marked cyst component. The serum alpha-fetoprotein (αFP) level was extremely high. Histological examination of specimens after subtotal removal revealed a primary mixed germ cell tumor with extensive yolk sac tumor elements, often referred to as an intracranial “yolk sac tumor.” The preoperative diagnosis of NGGCTs in unusual age and locations is extremely difficult. Clinicians should consider the possibility of NGGCTs, including yolk sac tumors, when intracranial tumors with unusual MRI findings are encountered. |
| format | Article |
| id | doaj-art-7e81a30a10ca4995b3703c2a875a5458 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-7e81a30a10ca4995b3703c2a875a54582025-02-03T01:22:47ZengWileyCase Reports in Surgery2090-69002090-69192012-01-01201210.1155/2012/473790473790Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an AdultToshihide Takahashi0Eiichi Ishikawa1Yosuke Masuda2Tetsuya Yamamoto3Taiki Sato4Makoto Shibuya5Akira Matsumura6Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, JapanDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, JapanDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, JapanDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, JapanDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, JapanDepartment of Pathology, Tokyo Medical University Ibaraki Medical Center, Ami, Ibaraki 300-0395, JapanDepartment of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, JapanIntracranial nongerminomatous germ cell tumors (NGGCTs) in unusual locations are extremely rare. Here, we report a case of a yolk sac tumor in the frontal lobe in a middle-aged patient. A 42-year-old man was admitted to our hospital for headache and nausea. Magnetic resonance imaging (MRI) showed an enhanced mass lesion with a marked cyst component. The serum alpha-fetoprotein (αFP) level was extremely high. Histological examination of specimens after subtotal removal revealed a primary mixed germ cell tumor with extensive yolk sac tumor elements, often referred to as an intracranial “yolk sac tumor.” The preoperative diagnosis of NGGCTs in unusual age and locations is extremely difficult. Clinicians should consider the possibility of NGGCTs, including yolk sac tumors, when intracranial tumors with unusual MRI findings are encountered.http://dx.doi.org/10.1155/2012/473790 |
| spellingShingle | Toshihide Takahashi Eiichi Ishikawa Yosuke Masuda Tetsuya Yamamoto Taiki Sato Makoto Shibuya Akira Matsumura Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult Case Reports in Surgery |
| title | Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult |
| title_full | Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult |
| title_fullStr | Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult |
| title_full_unstemmed | Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult |
| title_short | Mixed Germ Cell Tumor with Extensive Yolk Sac Tumor Elements in the Frontal Lobe of an Adult |
| title_sort | mixed germ cell tumor with extensive yolk sac tumor elements in the frontal lobe of an adult |
| url | http://dx.doi.org/10.1155/2012/473790 |
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