Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice.

Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice.

<h4>Background</h4>Astroglial cells are activated following injury and up-regulate the expression of the intermediate filament proteins glial fibrillary acidic protein (GFAP) and vimentin. Adult mice lacking the intermediate filament proteins GFAP and vimentin (GFAP(-/-)Vim(-/-)) show at...

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Main Authors: Katarina Järlestedt, Catherine I Rousset, Maryam Faiz, Ulrika Wilhelmsson, Anders Ståhlberg, Hana Sourkova, Marcela Pekna, Carina Mallard, Henrik Hagberg, Milos Pekny
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0010397&type=printable
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