The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients

By July 2021, the United States had over 34.4 million confirmed COVID-19 cases. Various cardiovascular manifestations of COVID-19 have been reported including ST-elevation myocardial infarction (STEMI), and there is concern that SARS-CoV-2 may be associated with a higher thrombus burden. We performe...

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Main Authors: Ju Young Bae, Khalil Ian Hussein, Christopher John Howes, John Francis Setaro
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2021/9915650
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author Ju Young Bae
Khalil Ian Hussein
Christopher John Howes
John Francis Setaro
author_facet Ju Young Bae
Khalil Ian Hussein
Christopher John Howes
John Francis Setaro
author_sort Ju Young Bae
collection DOAJ
description By July 2021, the United States had over 34.4 million confirmed COVID-19 cases. Various cardiovascular manifestations of COVID-19 have been reported including ST-elevation myocardial infarction (STEMI), and there is concern that SARS-CoV-2 may be associated with a higher thrombus burden. We performed a retrospective chart review of 535 adult patients with COVID-19 admitted at Yale-New Haven Health Greenwich Hospital from February 1, 2020, to May 13, 2020. All admitted patients had undergone testing for serum troponin I and various inflammatory markers, and we identified three patients who were diagnosed with acute STEMI. Data was collected via manual chart review and included patient demographics, comorbidities, laboratory tests, electrocardiogram (ECG) results, echocardiography results, diagnoses during hospitalization, inpatient therapies, and outcomes including length of hospital stay, revascularization results, and mortality. Three of our patients had obstructive coronary artery disease confirmed via angiography. One subject was noted to display vasospasm in addition to coronary atherosclerotic obstruction and refractory thrombus formation. Among our patients with COVID-19 and STEMI, presentations were variable in terms of timing of onset of ECG changes, age, gender, race, comorbidities, symptomology, and outcomes.
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spelling doaj-art-7e6fb7e62756405cbbb262821e08d67f2025-02-03T05:43:47ZengWileyCase Reports in Cardiology2090-64042090-64122021-01-01202110.1155/2021/99156509915650The Challenges of ST-Elevation Myocardial Infarction in COVID-19 PatientsJu Young Bae0Khalil Ian Hussein1Christopher John Howes2John Francis Setaro3Department of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USADepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USADepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USADepartment of Medicine, Greenwich Hospital, Yale-New Haven Health System, 5 Perryridge Road, Greenwich, CT 06830, USABy July 2021, the United States had over 34.4 million confirmed COVID-19 cases. Various cardiovascular manifestations of COVID-19 have been reported including ST-elevation myocardial infarction (STEMI), and there is concern that SARS-CoV-2 may be associated with a higher thrombus burden. We performed a retrospective chart review of 535 adult patients with COVID-19 admitted at Yale-New Haven Health Greenwich Hospital from February 1, 2020, to May 13, 2020. All admitted patients had undergone testing for serum troponin I and various inflammatory markers, and we identified three patients who were diagnosed with acute STEMI. Data was collected via manual chart review and included patient demographics, comorbidities, laboratory tests, electrocardiogram (ECG) results, echocardiography results, diagnoses during hospitalization, inpatient therapies, and outcomes including length of hospital stay, revascularization results, and mortality. Three of our patients had obstructive coronary artery disease confirmed via angiography. One subject was noted to display vasospasm in addition to coronary atherosclerotic obstruction and refractory thrombus formation. Among our patients with COVID-19 and STEMI, presentations were variable in terms of timing of onset of ECG changes, age, gender, race, comorbidities, symptomology, and outcomes.http://dx.doi.org/10.1155/2021/9915650
spellingShingle Ju Young Bae
Khalil Ian Hussein
Christopher John Howes
John Francis Setaro
The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
Case Reports in Cardiology
title The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
title_full The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
title_fullStr The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
title_full_unstemmed The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
title_short The Challenges of ST-Elevation Myocardial Infarction in COVID-19 Patients
title_sort challenges of st elevation myocardial infarction in covid 19 patients
url http://dx.doi.org/10.1155/2021/9915650
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