Tangeretin suppresses RANKL-induced osteoclastogenesis and alleviates postmenopausal osteoporosis by inhibiting Notch signaling

Tangeretin suppresses RANKL-induced osteoclastogenesis and alleviates postmenopausal osteoporosis by inhibiting Notch signaling

Background: Postmenopausal osteoporosis is characterized by osteoclast differentiation and bone loss. Tangeretin (TGN) is a natural product that possesses multiple pharmacological properties. However, its specific function in postmenopausal osteoporosis deserves further exploration. Methods: The in...

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Bibliographic Details
Main Authors: Tengfei Wu, Fang Wang, Changqing Ai, Li Li, Fan Wu
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Regenerative Therapy
Subjects:
Postmenopausal osteoporosis
TGN
Osteoclast differentiation
Notch signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320425000951
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