Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors

Isolated primary candidal infection of joint is extremely rare, with only a few reported cases. It occurs as a result of accidental implantations of fungus during traumatic procedures, such as surgery, and is usually reported in patients with predisposing factors such as immunosuppression, malignanc...

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Main Authors: Gun Woo Lee, Tae-Hun Kim, Jung-Hwan Son
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/375682
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author Gun Woo Lee
Tae-Hun Kim
Jung-Hwan Son
author_facet Gun Woo Lee
Tae-Hun Kim
Jung-Hwan Son
author_sort Gun Woo Lee
collection DOAJ
description Isolated primary candidal infection of joint is extremely rare, with only a few reported cases. It occurs as a result of accidental implantations of fungus during traumatic procedures, such as surgery, and is usually reported in patients with predisposing factors such as immunosuppression, malignancy, and drug abuse. If left untreated, irreversible deformity and pain with severe osteoarticular destruction occur. Thus, early diagnosis and treatment are important. This paper presents a case of 72-year-old man with primary C. guilliermondii infection of knee joint without predisposing factors and previous traumatic procedures, who was misdiagnosed with advanced degenerative osteoarthritis. Our case is the second case of primary C. guilliermondii arthritis of knee to be reported in the English-language literature and the first to be successfully treated with total knee arthroplasty following IV amphotericin B and oral fluconazole. Primary candidal infection of joint is generally asymptomatic or involves only mild pain and swelling in the affected knee. Thus, although the majority of knee joint infections are of a pyogenic or tuberculous origin, if a patient complains of mild pain and swelling in the knee and has mild signs of infection, the possibility of fungal infection should be considered.
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spelling doaj-art-7e4a4d88de104575abd6baf2704bfacc2025-02-03T05:57:08ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/375682375682Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing FactorsGun Woo Lee0Tae-Hun Kim1Jung-Hwan Son2Department of Orthopedic Surgery, Gospel Hospital, Kosin University, 34 Amnam-Dong, Seo-gu, Busan 602-702, Republic of KoreaDepartment of Orthopedic Surgery, Gospel Hospital, Kosin University, 34 Amnam-Dong, Seo-gu, Busan 602-702, Republic of KoreaDepartment of Orthopedic Surgery, Gospel Hospital, Kosin University, 34 Amnam-Dong, Seo-gu, Busan 602-702, Republic of KoreaIsolated primary candidal infection of joint is extremely rare, with only a few reported cases. It occurs as a result of accidental implantations of fungus during traumatic procedures, such as surgery, and is usually reported in patients with predisposing factors such as immunosuppression, malignancy, and drug abuse. If left untreated, irreversible deformity and pain with severe osteoarticular destruction occur. Thus, early diagnosis and treatment are important. This paper presents a case of 72-year-old man with primary C. guilliermondii infection of knee joint without predisposing factors and previous traumatic procedures, who was misdiagnosed with advanced degenerative osteoarthritis. Our case is the second case of primary C. guilliermondii arthritis of knee to be reported in the English-language literature and the first to be successfully treated with total knee arthroplasty following IV amphotericin B and oral fluconazole. Primary candidal infection of joint is generally asymptomatic or involves only mild pain and swelling in the affected knee. Thus, although the majority of knee joint infections are of a pyogenic or tuberculous origin, if a patient complains of mild pain and swelling in the knee and has mild signs of infection, the possibility of fungal infection should be considered.http://dx.doi.org/10.1155/2012/375682
spellingShingle Gun Woo Lee
Tae-Hun Kim
Jung-Hwan Son
Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
Case Reports in Medicine
title Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
title_full Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
title_fullStr Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
title_full_unstemmed Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
title_short Primary Candida guilliermondii Infection of the Knee in a Patient without Predisposing Factors
title_sort primary candida guilliermondii infection of the knee in a patient without predisposing factors
url http://dx.doi.org/10.1155/2012/375682
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