Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics
Apples are among the most economically vital crops growing worldwide. The present study aimed to analyze the variation in the content of key bioactive principles and antioxidative potential of novel apple genotypes (developed through breeding techniques) along with their correlation for possible the...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025005286 |
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| author | Syed Mudassir Jeelani Salwee Yasmin Ashiq Hussain Lone Javid Iqbal Mir Mohammad Irfan Vishal Dinkar Wasim Hassan Raja Sajad Un Nabi Mahendra Kumar Verma Geetika Malik Om Chand Sharma |
| author_facet | Syed Mudassir Jeelani Salwee Yasmin Ashiq Hussain Lone Javid Iqbal Mir Mohammad Irfan Vishal Dinkar Wasim Hassan Raja Sajad Un Nabi Mahendra Kumar Verma Geetika Malik Om Chand Sharma |
| author_sort | Syed Mudassir Jeelani |
| collection | DOAJ |
| description | Apples are among the most economically vital crops growing worldwide. The present study aimed to analyze the variation in the content of key bioactive principles and antioxidative potential of novel apple genotypes (developed through breeding techniques) along with their correlation for possible therapeutic insights. Using the HPLC method, the bioactive compounds of these apples were investigated, and their contribution to free radical scavenging activity by employing DPPH assay. HPLC analyses displayed concentration of bioactive compounds varies significantly among these genotypes with catechins, epicatechins, quercetin, and rutin were the key bioactive compounds. Principal Component Analysis results revealed a correlation between total phenolic content and antioxidative potential. It is also apparent that phenols are primary contributors to the antioxidant efficacy among the apple genotypes under investigation for potential therapeutic application. Besides, the study dispenses some valuable statistics for the production of novel apple genotypes having added phytochemicals for conventional and modern breeders. |
| format | Article |
| id | doaj-art-7e21a309ff6647e3ad5d204bfbb3b547 |
| institution | Kabale University |
| issn | 2405-8440 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj-art-7e21a309ff6647e3ad5d204bfbb3b5472025-02-02T05:29:02ZengElsevierHeliyon2405-84402025-01-01112e42148Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeuticsSyed Mudassir Jeelani0Salwee Yasmin1Ashiq Hussain Lone2Javid Iqbal Mir3Mohammad Irfan4Vishal Dinkar5Wasim Hassan Raja6Sajad Un Nabi7Mahendra Kumar Verma8Geetika Malik9Om Chand Sharma10Corresponding author.; ICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaCorresponding author.; ICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaICAR-Central Institute of Temperate Horticulture, Srinagar, Jammu & Kashmir, 191132, IndiaApples are among the most economically vital crops growing worldwide. The present study aimed to analyze the variation in the content of key bioactive principles and antioxidative potential of novel apple genotypes (developed through breeding techniques) along with their correlation for possible therapeutic insights. Using the HPLC method, the bioactive compounds of these apples were investigated, and their contribution to free radical scavenging activity by employing DPPH assay. HPLC analyses displayed concentration of bioactive compounds varies significantly among these genotypes with catechins, epicatechins, quercetin, and rutin were the key bioactive compounds. Principal Component Analysis results revealed a correlation between total phenolic content and antioxidative potential. It is also apparent that phenols are primary contributors to the antioxidant efficacy among the apple genotypes under investigation for potential therapeutic application. Besides, the study dispenses some valuable statistics for the production of novel apple genotypes having added phytochemicals for conventional and modern breeders.http://www.sciencedirect.com/science/article/pii/S2405844025005286Apple genotypesBioactive compoundsAntioxidative potentialDPPHPhenolicsPCA |
| spellingShingle | Syed Mudassir Jeelani Salwee Yasmin Ashiq Hussain Lone Javid Iqbal Mir Mohammad Irfan Vishal Dinkar Wasim Hassan Raja Sajad Un Nabi Mahendra Kumar Verma Geetika Malik Om Chand Sharma Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics Heliyon Apple genotypes Bioactive compounds Antioxidative potential DPPH Phenolics PCA |
| title | Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics |
| title_full | Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics |
| title_fullStr | Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics |
| title_full_unstemmed | Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics |
| title_short | Differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes: A correlative study for potential therapeutics |
| title_sort | differential quantity of key bioactive compounds and their antioxidative potential in novel apple genotypes a correlative study for potential therapeutics |
| topic | Apple genotypes Bioactive compounds Antioxidative potential DPPH Phenolics PCA |
| url | http://www.sciencedirect.com/science/article/pii/S2405844025005286 |
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