A child presenting with bullous emphysema

Background. Placental transmogrification of the lung (PTL) is a clinical spectrum varying from asymptomatic to severe pulmonary impairment; such as recurrent pneumothorax, bronchopneumonia, respiratory distress syndrome and chronic obstructive airway disease. PTL usually presents as a bullous...

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Main Authors: Beste Özsezen, Uğur Özçelik, Deniz Doğru, Ebru Yalçın, Diclehan Orhan, Tutku Soyer, Nagehan Emiralioğlu, Elnur Nurullayev, H Nursun Özcan, Meral Üner, Dilber Ademhan Tural, Nural Kiper
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2022-10-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/234
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author Beste Özsezen
Uğur Özçelik
Deniz Doğru
Ebru Yalçın
Diclehan Orhan
Tutku Soyer
Nagehan Emiralioğlu
Elnur Nurullayev
H Nursun Özcan
Meral Üner
Dilber Ademhan Tural
Nural Kiper
author_facet Beste Özsezen
Uğur Özçelik
Deniz Doğru
Ebru Yalçın
Diclehan Orhan
Tutku Soyer
Nagehan Emiralioğlu
Elnur Nurullayev
H Nursun Özcan
Meral Üner
Dilber Ademhan Tural
Nural Kiper
author_sort Beste Özsezen
collection DOAJ
description Background. Placental transmogrification of the lung (PTL) is a clinical spectrum varying from asymptomatic to severe pulmonary impairment; such as recurrent pneumothorax, bronchopneumonia, respiratory distress syndrome and chronic obstructive airway disease. PTL usually presents as a bullous lesion, and rarely can appear in nodule or cyst formation on chest imaging. PTL with giant bullous emphysema has a male preference, is more commonly unilateral and mostly affects one lobe, but can rarely involve more than one lobe. Case. Here we report a 13-year-old boy presenting with bullous emphysema and coexisting with a borderline testicular tumor. He had no complaints of cough, sputum, or shortness of breath. He had a past medical history of pneumonia five years ago. In order to elucidate the underlying lung pathology, a wedge lung biopsy was performed and the patient was diagnosed with PTL. Scrotum ultrasonography was performed because of hydrocele in both testes, and bilateral epididymal cysts with papillary solid projections were reported. Pathological examination of the epididymal tumor revealed a `Mullerian type borderline epithelial neoplasm` which is an analogue of the ovarian serous borderline tumor. Conclusions. In conclusion, we reported the youngest PTL case in the literature, a rare disease with unknown pathophysiology, presenting as bullous emphysema and coincidental Mullerian type borderline epithelial neoplasm. It is important to diagnose placental transmogrification of the lung in a child with bullous emphysema because compared to other cystic lung diseases it is a benign disease and if no additional malignity exists, lobectomy or pneumonectomy is the cure for the disease.
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issn 0041-4301
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language English
publishDate 2022-10-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-7e07b51addbd4c74bda1f0035e718f1e2025-08-20T02:55:21ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212022-10-0164510.24953/turkjped.2021.5515A child presenting with bullous emphysemaBeste Özsezen0Uğur Özçelik1Deniz Doğru2Ebru Yalçın3Diclehan Orhan4Tutku Soyer5Nagehan Emiralioğlu6Elnur Nurullayev7H Nursun Özcan8Meral Üner9Dilber Ademhan Tural10Nural Kiper11Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Radiology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Surgery, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Surgery, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Radiology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pathology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye.Departments of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Türkiye. Background. Placental transmogrification of the lung (PTL) is a clinical spectrum varying from asymptomatic to severe pulmonary impairment; such as recurrent pneumothorax, bronchopneumonia, respiratory distress syndrome and chronic obstructive airway disease. PTL usually presents as a bullous lesion, and rarely can appear in nodule or cyst formation on chest imaging. PTL with giant bullous emphysema has a male preference, is more commonly unilateral and mostly affects one lobe, but can rarely involve more than one lobe. Case. Here we report a 13-year-old boy presenting with bullous emphysema and coexisting with a borderline testicular tumor. He had no complaints of cough, sputum, or shortness of breath. He had a past medical history of pneumonia five years ago. In order to elucidate the underlying lung pathology, a wedge lung biopsy was performed and the patient was diagnosed with PTL. Scrotum ultrasonography was performed because of hydrocele in both testes, and bilateral epididymal cysts with papillary solid projections were reported. Pathological examination of the epididymal tumor revealed a `Mullerian type borderline epithelial neoplasm` which is an analogue of the ovarian serous borderline tumor. Conclusions. In conclusion, we reported the youngest PTL case in the literature, a rare disease with unknown pathophysiology, presenting as bullous emphysema and coincidental Mullerian type borderline epithelial neoplasm. It is important to diagnose placental transmogrification of the lung in a child with bullous emphysema because compared to other cystic lung diseases it is a benign disease and if no additional malignity exists, lobectomy or pneumonectomy is the cure for the disease. https://turkjpediatr.org/article/view/234Mullerian type borderline epithelial neoplasmbullous emphysemachildhydroceleplacental transmogrification
spellingShingle Beste Özsezen
Uğur Özçelik
Deniz Doğru
Ebru Yalçın
Diclehan Orhan
Tutku Soyer
Nagehan Emiralioğlu
Elnur Nurullayev
H Nursun Özcan
Meral Üner
Dilber Ademhan Tural
Nural Kiper
A child presenting with bullous emphysema
The Turkish Journal of Pediatrics
Mullerian type borderline epithelial neoplasm
bullous emphysema
child
hydrocele
placental transmogrification
title A child presenting with bullous emphysema
title_full A child presenting with bullous emphysema
title_fullStr A child presenting with bullous emphysema
title_full_unstemmed A child presenting with bullous emphysema
title_short A child presenting with bullous emphysema
title_sort child presenting with bullous emphysema
topic Mullerian type borderline epithelial neoplasm
bullous emphysema
child
hydrocele
placental transmogrification
url https://turkjpediatr.org/article/view/234
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