Metalation of Olefinic Positions in Norbornadiene: Enhancement and Attenuation of Kinetic CH-Acidities by a Neighboring Enesilane Moiety

When treated with butyllithium in the presence of sodium or potassium tert-butoxide, 2-trimethylsilyl- and 2-triethylsilyl-norbornadiene undergo hydrogen/metal-exchange mainly at the 5-position. The latter position is found to be slightly activated relative to unsubstituted norbornadiene while the...

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Bibliographic Details
Main Authors: Alessandro Mordini, Manfred Schlosser
Format: Article
Language:deu
Published: Swiss Chemical Society 1986-09-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9746
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Summary:When treated with butyllithium in the presence of sodium or potassium tert-butoxide, 2-trimethylsilyl- and 2-triethylsilyl-norbornadiene undergo hydrogen/metal-exchange mainly at the 5-position. The latter position is found to be slightly activated relative to unsubstituted norbornadiene while the two other olefinic positions prove to be quite inert. Two side reactions are observed: the metalation of silicon-attached methyl groups and the replacement of the entire trialkylsilyl group by a metal atom.
ISSN:0009-4293
2673-2424