Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review

Intrahepatic cholangiocarcinoma, an increasingly recognized primary tumour of the liver, is associated with a very poor prognosis. A patient with this tumour who presented with Budd-Chiari syndrome (the first to the authors' knowledge in Western literature and only the third patient overall) se...

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Main Authors: Joanna K Law, Jenny Davis, Anne Buckley, Baljinder Salh
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2005/943269
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author Joanna K Law
Jenny Davis
Anne Buckley
Baljinder Salh
author_facet Joanna K Law
Jenny Davis
Anne Buckley
Baljinder Salh
author_sort Joanna K Law
collection DOAJ
description Intrahepatic cholangiocarcinoma, an increasingly recognized primary tumour of the liver, is associated with a very poor prognosis. A patient with this tumour who presented with Budd-Chiari syndrome (the first to the authors' knowledge in Western literature and only the third patient overall) secondary to extensive thrombosis in his inferior vena cava extending from the right atrium down to his iliac vessels is described. Neither curative nor palliative intervention was deemed to be an option in this patient, who deteriorated rapidly while on anti-coagulants. Postmortem examination confirmed the radiological findings, and histological analysis revealed characteristic appearances of this tumour within the biliary tree and invasion into the inferior vena cava. Furthermore, biliary dysplasia, which can be a precursor to this cancer, was also noted within some of the bile ducts.
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series Canadian Journal of Gastroenterology
spelling doaj-art-7dffcaf68c9245f08114af905ff349e02025-02-03T01:13:05ZengWileyCanadian Journal of Gastroenterology0835-79002005-01-01191272372810.1155/2005/943269Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature ReviewJoanna K Law0Jenny Davis1Anne Buckley2Baljinder Salh3Department of Medicine, Vancouver Hospital and Health Sciences Centre, Vancouver, British Columbia, CanadaDepartment of Pathology, Vancouver Hospital and Health Sciences Centre, Vancouver, British Columbia, CanadaDepartment of Radiology, Vancouver Hospital and Health Sciences Centre, Vancouver, British Columbia, CanadaDepartment of Medicine, Vancouver Hospital and Health Sciences Centre, Vancouver, British Columbia, CanadaIntrahepatic cholangiocarcinoma, an increasingly recognized primary tumour of the liver, is associated with a very poor prognosis. A patient with this tumour who presented with Budd-Chiari syndrome (the first to the authors' knowledge in Western literature and only the third patient overall) secondary to extensive thrombosis in his inferior vena cava extending from the right atrium down to his iliac vessels is described. Neither curative nor palliative intervention was deemed to be an option in this patient, who deteriorated rapidly while on anti-coagulants. Postmortem examination confirmed the radiological findings, and histological analysis revealed characteristic appearances of this tumour within the biliary tree and invasion into the inferior vena cava. Furthermore, biliary dysplasia, which can be a precursor to this cancer, was also noted within some of the bile ducts.http://dx.doi.org/10.1155/2005/943269
spellingShingle Joanna K Law
Jenny Davis
Anne Buckley
Baljinder Salh
Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review
Canadian Journal of Gastroenterology
title Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review
title_full Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review
title_fullStr Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review
title_full_unstemmed Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review
title_short Intrahepatic Cholangiocarcinoma Presenting as the Budd-Chiari Syndrome: A Case Report and Literature Review
title_sort intrahepatic cholangiocarcinoma presenting as the budd chiari syndrome a case report and literature review
url http://dx.doi.org/10.1155/2005/943269
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AT annebuckley intrahepaticcholangiocarcinomapresentingasthebuddchiarisyndromeacasereportandliteraturereview
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