A retinoic acid:YAP1 signaling axis controls atrial lineage commitment

A retinoic acid:YAP1 signaling axis controls atrial lineage commitment

Summary: In cardiac progenitor cells (CPCs), retinoic acid (RA) signaling induces atrial lineage gene expression and acquisition of an atrial cell fate. To achieve this, RA coordinates a complex regulatory network of downstream effectors that is not fully identified. To address this gap, we applied...

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Bibliographic Details
Main Authors: Elizabeth Abraham, Aleksandra Kostina, Brett Volmert, Thomas Roule, Ling Huang, Jingting Yu, April E. Williams, Emily Megill, Aidan Douglas, Olivia M. Pericak, Alex Morris, Eleonora Stronati, Arantza Larrinaga-Zamanillo, Raquel Fueyo, Mikel Zubillaga, Mark D. Andrake, Naiara Akizu, Aitor Aguirre, Conchi Estaras
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Cell Reports
Subjects:
CP: Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725004589
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