Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series
Abstract Background Long bones are one of the most common sites involved in fibrous dysplasia. In some cases, there is no deformity, but patients suffer sustained or intermittent dull pain. Case presentation Since 2021, a retrospective case series of seven East Asian patients with fibrous dysplasia...
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BMC
2025-05-01
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| Series: | Journal of Medical Case Reports |
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| Online Access: | https://doi.org/10.1186/s13256-025-05261-8 |
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| author | Man-hua Liu Hong-Xia Zhu Lei Fu Lun-Li Xie |
| author_facet | Man-hua Liu Hong-Xia Zhu Lei Fu Lun-Li Xie |
| author_sort | Man-hua Liu |
| collection | DOAJ |
| description | Abstract Background Long bones are one of the most common sites involved in fibrous dysplasia. In some cases, there is no deformity, but patients suffer sustained or intermittent dull pain. Case presentation Since 2021, a retrospective case series of seven East Asian patients with fibrous dysplasia of a long bone without severe deformity were reviewed. These patients include three male and four female patients, with an average age of 32.7 years (range 4–70 years). Fibrous dysplasia was diagnosed at a total of three different sites in these seven cases including five femurs (71.4%), one humerus (14.3%), and one fibular bone (14.3%). All patients received treatment with allogenic bone grafting or cortical strut grafting with or without compression locking and screw fixation. The radiological and clinicopathologic presentation was analyzed by the surgeon. There were no cases with polyostotic forms or fibrous dysplasia in combination with extraskeletal disease. The presenting complaint was pain in all cases and localized swelling in 1 (14.3%) of the cases. Conclusions Autogenous fibular cortical strut grafting and compression hip screw fixation achieved good postoperative function and provided an early return to work for adult patients with fibrous dysplasia of the femoral neck with mild but prolonged symptoms. However, total hip replacement may be a suitable method for fibrous dysplasia of the femoral neck accompanied by pathological fracture. |
| format | Article |
| id | doaj-art-7df477285ec64d00aab767e406566eae |
| institution | OA Journals |
| issn | 1752-1947 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj-art-7df477285ec64d00aab767e406566eae2025-08-20T01:51:32ZengBMCJournal of Medical Case Reports1752-19472025-05-0119111310.1186/s13256-025-05261-8Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case seriesMan-hua Liu0Hong-Xia Zhu1Lei Fu2Lun-Li Xie3Department of Joint and Hand Orthopedics, Hunan University of Medicine General HospitalDepartment of Traumatic Orthopedics, Hunan University of Medicine General HospitalDepartment of Joint and Hand Orthopedics, Hunan University of Medicine General HospitalDepartment of Joint and Hand Orthopedics, Hunan University of Medicine General HospitalAbstract Background Long bones are one of the most common sites involved in fibrous dysplasia. In some cases, there is no deformity, but patients suffer sustained or intermittent dull pain. Case presentation Since 2021, a retrospective case series of seven East Asian patients with fibrous dysplasia of a long bone without severe deformity were reviewed. These patients include three male and four female patients, with an average age of 32.7 years (range 4–70 years). Fibrous dysplasia was diagnosed at a total of three different sites in these seven cases including five femurs (71.4%), one humerus (14.3%), and one fibular bone (14.3%). All patients received treatment with allogenic bone grafting or cortical strut grafting with or without compression locking and screw fixation. The radiological and clinicopathologic presentation was analyzed by the surgeon. There were no cases with polyostotic forms or fibrous dysplasia in combination with extraskeletal disease. The presenting complaint was pain in all cases and localized swelling in 1 (14.3%) of the cases. Conclusions Autogenous fibular cortical strut grafting and compression hip screw fixation achieved good postoperative function and provided an early return to work for adult patients with fibrous dysplasia of the femoral neck with mild but prolonged symptoms. However, total hip replacement may be a suitable method for fibrous dysplasia of the femoral neck accompanied by pathological fracture.https://doi.org/10.1186/s13256-025-05261-8Fibrous dysplasiaRadiological presentationClinicopathologic presentationAllogenic bone graftingSurgical treatmentPathological fracture |
| spellingShingle | Man-hua Liu Hong-Xia Zhu Lei Fu Lun-Li Xie Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series Journal of Medical Case Reports Fibrous dysplasia Radiological presentation Clinicopathologic presentation Allogenic bone grafting Surgical treatment Pathological fracture |
| title | Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series |
| title_full | Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series |
| title_fullStr | Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series |
| title_full_unstemmed | Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series |
| title_short | Treatment approach with clinical follow-up in monostotic fibrous dysplasia: a case series |
| title_sort | treatment approach with clinical follow up in monostotic fibrous dysplasia a case series |
| topic | Fibrous dysplasia Radiological presentation Clinicopathologic presentation Allogenic bone grafting Surgical treatment Pathological fracture |
| url | https://doi.org/10.1186/s13256-025-05261-8 |
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