Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease
Objective. To examine the associations of dietary glycemic index (GI) and dietary glycemic load (GL) with blood lipid concentrations and coronary heart disease (CHD) in nondiabetic participants in the Health Worker Cohort Study (HWCS). Materials and Methods. A cross-sectional analysis was performed,...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
|
| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2010/170680 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832549587128156160 |
|---|---|
| author | Edgar Denova-Gutiérrez Gerardo Huitrón-Bravo Juan O. Talavera Susana Castañón Katia Gallegos-Carrillo Yvonne Flores Jorge Salmerón |
| author_facet | Edgar Denova-Gutiérrez Gerardo Huitrón-Bravo Juan O. Talavera Susana Castañón Katia Gallegos-Carrillo Yvonne Flores Jorge Salmerón |
| author_sort | Edgar Denova-Gutiérrez |
| collection | DOAJ |
| description | Objective. To examine the associations of dietary glycemic index (GI) and dietary glycemic load (GL) with blood lipid concentrations and coronary heart disease (CHD) in nondiabetic participants in the Health Worker Cohort Study (HWCS). Materials and Methods. A cross-sectional analysis was performed, using data from adults who participated in the HWCS baseline assessment. We collected information on participants' socio-demographic conditions, dietary patterns and physical activity via self-administered questionnaires. Dietary GI and dietary GL were measured using a validated food frequency questionnaire. Anthropometric and clinical measurements were assessed with standardized procedures. CHD risk was estimated according to the sex-specific Framingham prediction algorithms. Results. IIn the 5,830 individuals aged 20 to 70 who were evaluated, dietary GI and GL were significantly associated with HDL-C, LDL-C, LDL-C/HDL-C ratio, and triglycerides serum levels. Subjects with high dietary GI have a relative risk of 1.56 (CI 95%; 1.13–2.14), and those with high dietary GL have a relative risk of 2.64 (CI 95%; 1.15–6.58) of having an elevated CHD risk than those who had low dietary GI and GL. Conclusions. Our results suggest that high dietary GI and dietary GL could have an unfavorable effect on serum lipid levels, which are in turn associated with a higher CHD risk. |
| format | Article |
| id | doaj-art-7ddb6cd1446c492381ddadb809a6d12d |
| institution | Kabale University |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-7ddb6cd1446c492381ddadb809a6d12d2025-02-03T06:10:52ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322010-01-01201010.1155/2010/170680170680Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart DiseaseEdgar Denova-Gutiérrez0Gerardo Huitrón-Bravo1Juan O. Talavera2Susana Castañón3Katia Gallegos-Carrillo4Yvonne Flores5Jorge Salmerón6Centro de Investigación en Ciencias Médicas, Universidad Autónoma del Estado de México, 50130 Toluca Estado de México, MexicoUnidad de Investigación Médica en Epidemiología Clínica, Hospital de Especialidades CMN SXXI, 06720 México, MexicoCentro de Investigación en Ciencias Médicas, Universidad Autónoma del Estado de México, 50130 Toluca Estado de México, MexicoUnidad de Investigación Médica en Epidemiología Clínica, Hospital de Especialidades CMN SXXI, 06720 México, MexicoUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social, 65450 Cuernavaca Morelos, MexicoUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social, 65450 Cuernavaca Morelos, MexicoUnidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social, 65450 Cuernavaca Morelos, MexicoObjective. To examine the associations of dietary glycemic index (GI) and dietary glycemic load (GL) with blood lipid concentrations and coronary heart disease (CHD) in nondiabetic participants in the Health Worker Cohort Study (HWCS). Materials and Methods. A cross-sectional analysis was performed, using data from adults who participated in the HWCS baseline assessment. We collected information on participants' socio-demographic conditions, dietary patterns and physical activity via self-administered questionnaires. Dietary GI and dietary GL were measured using a validated food frequency questionnaire. Anthropometric and clinical measurements were assessed with standardized procedures. CHD risk was estimated according to the sex-specific Framingham prediction algorithms. Results. IIn the 5,830 individuals aged 20 to 70 who were evaluated, dietary GI and GL were significantly associated with HDL-C, LDL-C, LDL-C/HDL-C ratio, and triglycerides serum levels. Subjects with high dietary GI have a relative risk of 1.56 (CI 95%; 1.13–2.14), and those with high dietary GL have a relative risk of 2.64 (CI 95%; 1.15–6.58) of having an elevated CHD risk than those who had low dietary GI and GL. Conclusions. Our results suggest that high dietary GI and dietary GL could have an unfavorable effect on serum lipid levels, which are in turn associated with a higher CHD risk.http://dx.doi.org/10.1155/2010/170680 |
| spellingShingle | Edgar Denova-Gutiérrez Gerardo Huitrón-Bravo Juan O. Talavera Susana Castañón Katia Gallegos-Carrillo Yvonne Flores Jorge Salmerón Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease Journal of Nutrition and Metabolism |
| title | Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease |
| title_full | Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease |
| title_fullStr | Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease |
| title_full_unstemmed | Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease |
| title_short | Dietary Glycemic Index, Dietary Glycemic Load, Blood Lipids, and Coronary Heart Disease |
| title_sort | dietary glycemic index dietary glycemic load blood lipids and coronary heart disease |
| url | http://dx.doi.org/10.1155/2010/170680 |
| work_keys_str_mv | AT edgardenovagutierrez dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease AT gerardohuitronbravo dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease AT juanotalavera dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease AT susanacastanon dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease AT katiagallegoscarrillo dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease AT yvonneflores dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease AT jorgesalmeron dietaryglycemicindexdietaryglycemicloadbloodlipidsandcoronaryheartdisease |