Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis
Introduction. Lymphoma of the appendix is a rare cause of acute appendicitis; however, acute appendicitis is a common first manifestation of appendiceal lymphomas. Cytotoxic peripheral T cell lymphoma (PTCL) is a type of aggressive non-Hodgkin lymphoma that portends a generally poor outcome. Cytotox...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/8569426 |
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| author | Negin Rahmani Yahya Daneshbod Hadi Mirfazaelian Elnaz Vahidi Sadegh Shirian |
| author_facet | Negin Rahmani Yahya Daneshbod Hadi Mirfazaelian Elnaz Vahidi Sadegh Shirian |
| author_sort | Negin Rahmani |
| collection | DOAJ |
| description | Introduction. Lymphoma of the appendix is a rare cause of acute appendicitis; however, acute appendicitis is a common first manifestation of appendiceal lymphomas. Cytotoxic peripheral T cell lymphoma (PTCL) is a type of aggressive non-Hodgkin lymphoma that portends a generally poor outcome. Cytotoxic PTCL of the appendix is extremely rare with few cases reported in the literature. Case Presentation. This is the report of a 23-year-old man who had experienced lower abdominal pain for three months before presenting to the emergency department with severe right lower abdominal pain, nausea, vomiting, and anorexia since the day prior to admission. The patient was diagnosed with acute appendicitis, and the pathology report confirmed cytotoxic PTCL of the appendix. Conclusion. Patients with appendiceal PTCL commonly present with signs and symptoms of acute appendicitis due to luminal obstruction by the tumor. Therefore, appendiceal tumors such as PTCL should be considered in the differential diagnosis of patients presenting as acute appendicitis. In addition, since there is no standard chemotherapy regimen for cytotoxic PTCL, this and other case reports hopefully help in providing the clinical evidence needed for establishing appropriate treatment guidelines. |
| format | Article |
| id | doaj-art-7dd2482b0ba248979e168fb9e80d0af6 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-7dd2482b0ba248979e168fb9e80d0af62025-02-03T06:46:53ZengWileyCase Reports in Oncological Medicine2090-67062090-67142020-01-01202010.1155/2020/85694268569426Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute AppendicitisNegin Rahmani0Yahya Daneshbod1Hadi Mirfazaelian2Elnaz Vahidi3Sadegh Shirian4Shiraz University of Medical Sciences, Shiraz, IranShiraz Molecular Pathology Research Center, Dr. Daneshbod Lab, Shiraz, IranEmergency Medicine Department, Tehran University of Medical Sciences, Tehran, IranEmergency Medicine Department, Tehran University of Medical Sciences, Tehran, IranDepartment of Pathology, School of Veterinary Medicine, Shahrekord University, Shahrekord, IranIntroduction. Lymphoma of the appendix is a rare cause of acute appendicitis; however, acute appendicitis is a common first manifestation of appendiceal lymphomas. Cytotoxic peripheral T cell lymphoma (PTCL) is a type of aggressive non-Hodgkin lymphoma that portends a generally poor outcome. Cytotoxic PTCL of the appendix is extremely rare with few cases reported in the literature. Case Presentation. This is the report of a 23-year-old man who had experienced lower abdominal pain for three months before presenting to the emergency department with severe right lower abdominal pain, nausea, vomiting, and anorexia since the day prior to admission. The patient was diagnosed with acute appendicitis, and the pathology report confirmed cytotoxic PTCL of the appendix. Conclusion. Patients with appendiceal PTCL commonly present with signs and symptoms of acute appendicitis due to luminal obstruction by the tumor. Therefore, appendiceal tumors such as PTCL should be considered in the differential diagnosis of patients presenting as acute appendicitis. In addition, since there is no standard chemotherapy regimen for cytotoxic PTCL, this and other case reports hopefully help in providing the clinical evidence needed for establishing appropriate treatment guidelines.http://dx.doi.org/10.1155/2020/8569426 |
| spellingShingle | Negin Rahmani Yahya Daneshbod Hadi Mirfazaelian Elnaz Vahidi Sadegh Shirian Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis Case Reports in Oncological Medicine |
| title | Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis |
| title_full | Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis |
| title_fullStr | Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis |
| title_full_unstemmed | Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis |
| title_short | Peripheral Cytotoxic T Cell Lymphoma of the Appendix Presenting as Acute Appendicitis |
| title_sort | peripheral cytotoxic t cell lymphoma of the appendix presenting as acute appendicitis |
| url | http://dx.doi.org/10.1155/2020/8569426 |
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