Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review
Parenteral Nutrition (PN) is a valuable life saving intervention which can improve the nutritional status of hospitalized malnourished patients. PN is associated with complications including the development of hyperglycemia. This paper aims to provide a descriptive systematic review regarding the ef...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2011/760720 |
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| author | Puja Rajender Kumar Pam Crotty Maitreyi Raman |
| author_facet | Puja Rajender Kumar Pam Crotty Maitreyi Raman |
| author_sort | Puja Rajender Kumar |
| collection | DOAJ |
| description | Parenteral Nutrition (PN) is a valuable life saving intervention which can improve the nutritional status of hospitalized malnourished patients. PN is associated with complications including the development of hyperglycemia. This paper aims to provide a descriptive systematic review regarding the effects of PN-induced hyperglycemia in hospitalized patients, either in the intensive care unit or ward, while formulating and complementing existing guidelines on the administration of PN and glucose monitoring in hospitalized patients. Medline and Pubmed were searched for relevant articles describing complications arising from the development of hyperglycemia in patients receiving PN; four relevant studies were identified in the search. These articles had different glycemic targets and patient populations, and their protocols varied with regards to glycemic control. However, there was consistency regarding the association between hyperglycemia and mortality in patients receiving PN. These studies highlight the need for guidelines regarding monitoring and initiation of therapy in hyperglycemic patients. Unfortunately, all the currently available studies are retrospective in design; a large, prospective, randomized controlled trial regarding glycemic control in patients receiving PN is required for the development of standardized protocols. |
| format | Article |
| id | doaj-art-7db6f10cdac44f76960fadfb2b02586a |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-7db6f10cdac44f76960fadfb2b02586a2025-02-03T01:13:12ZengWileyGastroenterology Research and Practice1687-61211687-630X2011-01-01201110.1155/2011/760720760720Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A ReviewPuja Rajender Kumar0Pam Crotty1Maitreyi Raman2Division of Gastroenterology, Department of Medicine, University of Calgary, 6D26, Teaching, Research and Wellness Building, 3280 Hospital Drive N.W., Calgary, AB, T2N 4N1, CanadaDivision of Gastroenterology, Department of Medicine, University of Calgary, 6D26, Teaching, Research and Wellness Building, 3280 Hospital Drive N.W., Calgary, AB, T2N 4N1, CanadaDivision of Gastroenterology, Department of Medicine, University of Calgary, 6D26, Teaching, Research and Wellness Building, 3280 Hospital Drive N.W., Calgary, AB, T2N 4N1, CanadaParenteral Nutrition (PN) is a valuable life saving intervention which can improve the nutritional status of hospitalized malnourished patients. PN is associated with complications including the development of hyperglycemia. This paper aims to provide a descriptive systematic review regarding the effects of PN-induced hyperglycemia in hospitalized patients, either in the intensive care unit or ward, while formulating and complementing existing guidelines on the administration of PN and glucose monitoring in hospitalized patients. Medline and Pubmed were searched for relevant articles describing complications arising from the development of hyperglycemia in patients receiving PN; four relevant studies were identified in the search. These articles had different glycemic targets and patient populations, and their protocols varied with regards to glycemic control. However, there was consistency regarding the association between hyperglycemia and mortality in patients receiving PN. These studies highlight the need for guidelines regarding monitoring and initiation of therapy in hyperglycemic patients. Unfortunately, all the currently available studies are retrospective in design; a large, prospective, randomized controlled trial regarding glycemic control in patients receiving PN is required for the development of standardized protocols.http://dx.doi.org/10.1155/2011/760720 |
| spellingShingle | Puja Rajender Kumar Pam Crotty Maitreyi Raman Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review Gastroenterology Research and Practice |
| title | Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review |
| title_full | Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review |
| title_fullStr | Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review |
| title_full_unstemmed | Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review |
| title_short | Hyperglycemia in Hospitalized Patients Receiving Parental Nutrition Is Associated with Increased Morbidity and Mortality: A Review |
| title_sort | hyperglycemia in hospitalized patients receiving parental nutrition is associated with increased morbidity and mortality a review |
| url | http://dx.doi.org/10.1155/2011/760720 |
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