Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper
We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl2 and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 mola...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2018/2467463 |
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| author | Anshul Singh Ashu Chaudhary |
| author_facet | Anshul Singh Ashu Chaudhary |
| author_sort | Anshul Singh |
| collection | DOAJ |
| description | We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl2 and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats. |
| format | Article |
| id | doaj-art-7db6e495c22c47a7a3aad425cc574094 |
| institution | Kabale University |
| issn | 1565-3633 1687-479X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-7db6e495c22c47a7a3aad425cc5740942025-02-03T01:28:13ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2018-01-01201810.1155/2018/24674632467463Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent CopperAnshul Singh0Ashu Chaudhary1Department of Chemistry, Kurukshetra University, Kurukshetra 136 119, IndiaDepartment of Chemistry, Kurukshetra University, Kurukshetra 136 119, IndiaWe present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl2 and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats.http://dx.doi.org/10.1155/2018/2467463 |
| spellingShingle | Anshul Singh Ashu Chaudhary Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper Bioinorganic Chemistry and Applications |
| title | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
| title_full | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
| title_fullStr | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
| title_full_unstemmed | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
| title_short | Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper |
| title_sort | synthesis characterization and biological evaluation of unimetallic and heterobimetallic complexes of bivalent copper |
| url | http://dx.doi.org/10.1155/2018/2467463 |
| work_keys_str_mv | AT anshulsingh synthesischaracterizationandbiologicalevaluationofunimetallicandheterobimetalliccomplexesofbivalentcopper AT ashuchaudhary synthesischaracterizationandbiologicalevaluationofunimetallicandheterobimetalliccomplexesofbivalentcopper |