Tetrandrine slows disease progression on high-resolution computed tomography and lung function decline in artificial stone-associated silicosis: a retrospective cohort study

Tetrandrine slows disease progression on high-resolution computed tomography and lung function decline in artificial stone-associated silicosis: a retrospective cohort study

Abstract Background Silicosis, a progressive fibrotic lung disease caused by silica dust inhalation, is a significant occupational health concern, particularly among artificial quartz stone workers. Tetrandrine, a bisbenzylisoquinoline alkaloid, is the only plant-derived drug approved for the treatm...

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Bibliographic Details
Main Authors: Shaowei Zhou, Jin Shi, Zidan Chen, Luqin Bian, Limin Huang, Ling Mao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Pulmonary Medicine
Subjects:
Antifibrotic agents
Silicosis
Benzylisoquinolines
Computed tomography
Pulmonary function tests
Online Access:https://doi.org/10.1186/s12890-025-03821-8
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https://doi.org/10.1186/s12890-025-03821-8

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