Cancer, Natural Products and Nanodrug Delivery Systems

As an offshoot of nanotechnology, nanomedicine has made great impact in the field of pharmaceutical and biomedical sciences by achieving breakthroughs in therapeutics and diagnostics of diseases in living organisms. One of the promising breakthroughs is the application of natural product-based nano...

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Main Authors: Yong Sze Ong, Loh Teng-Hern Tan
Format: Article
Language:English
Published: HH Publisher 2020-06-01
Series:Progress in Microbes and Molecular Biology
Online Access:https://journals.hh-publisher.com/index.php/pmmb/article/view/289
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author Yong Sze Ong
Loh Teng-Hern Tan
author_facet Yong Sze Ong
Loh Teng-Hern Tan
author_sort Yong Sze Ong
collection DOAJ
description As an offshoot of nanotechnology, nanomedicine has made great impact in the field of pharmaceutical and biomedical sciences by achieving breakthroughs in therapeutics and diagnostics of diseases in living organisms. One of the promising breakthroughs is the application of natural product-based nanoformulations for the treatment of various human diseases, such as cancer. Principally, the nanoparticle-based drug delivery system (NDDS) aims to overcome the limitations of conventional drug delivery system. NDDS improves the in vivo pharmacological and therapeutic properties of the poorly soluble drugs by dissolving, encapsulating, absorbing and/or attaching the drugs with the matrices of the nanoparticles. The nanoparticles that act as drug reservoirs also aim to control the drug release, enhance the drug uptake by targeted delivery and protect the drug against enzymatic degradation. This review presents a summary of the integration of nanotechnology and phytotherapy to achieve an improved pharmacological response and better clinical outcome in patients undergoing chemotherapy.
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series Progress in Microbes and Molecular Biology
spelling doaj-art-7d8ed9a7631d4156ab17e6d6e81ea5c92025-02-04T08:37:04ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492020-06-013110.36877/pmmb.a0000089Cancer, Natural Products and Nanodrug Delivery SystemsYong Sze OngLoh Teng-Hern Tan As an offshoot of nanotechnology, nanomedicine has made great impact in the field of pharmaceutical and biomedical sciences by achieving breakthroughs in therapeutics and diagnostics of diseases in living organisms. One of the promising breakthroughs is the application of natural product-based nanoformulations for the treatment of various human diseases, such as cancer. Principally, the nanoparticle-based drug delivery system (NDDS) aims to overcome the limitations of conventional drug delivery system. NDDS improves the in vivo pharmacological and therapeutic properties of the poorly soluble drugs by dissolving, encapsulating, absorbing and/or attaching the drugs with the matrices of the nanoparticles. The nanoparticles that act as drug reservoirs also aim to control the drug release, enhance the drug uptake by targeted delivery and protect the drug against enzymatic degradation. This review presents a summary of the integration of nanotechnology and phytotherapy to achieve an improved pharmacological response and better clinical outcome in patients undergoing chemotherapy. https://journals.hh-publisher.com/index.php/pmmb/article/view/289
spellingShingle Yong Sze Ong
Loh Teng-Hern Tan
Cancer, Natural Products and Nanodrug Delivery Systems
Progress in Microbes and Molecular Biology
title Cancer, Natural Products and Nanodrug Delivery Systems
title_full Cancer, Natural Products and Nanodrug Delivery Systems
title_fullStr Cancer, Natural Products and Nanodrug Delivery Systems
title_full_unstemmed Cancer, Natural Products and Nanodrug Delivery Systems
title_short Cancer, Natural Products and Nanodrug Delivery Systems
title_sort cancer natural products and nanodrug delivery systems
url https://journals.hh-publisher.com/index.php/pmmb/article/view/289
work_keys_str_mv AT yongszeong cancernaturalproductsandnanodrugdeliverysystems
AT lohtengherntan cancernaturalproductsandnanodrugdeliverysystems