Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication
Aortic dissection is a potentially fatal but rare disease characterized by an aortic intimal tear with blood passing into the media creating a false lumen and with resultant high mortality depending on the location of dissection if not aggressively treated. Cocaine users are known to have a higher i...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2011/174132 |
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| author | Fahad Javed Alexandre Miguel Benjo Kiran Reddy Muhammad Shoaib Akram Shahzeb Afsar Khan Manpreet Singh Sabharwal Girish Nadkarni Emad F. Aziz Eyal Herzog |
| author_facet | Fahad Javed Alexandre Miguel Benjo Kiran Reddy Muhammad Shoaib Akram Shahzeb Afsar Khan Manpreet Singh Sabharwal Girish Nadkarni Emad F. Aziz Eyal Herzog |
| author_sort | Fahad Javed |
| collection | DOAJ |
| description | Aortic dissection is a potentially fatal but rare disease characterized by an aortic intimal tear with blood passing into the media creating a false lumen and with resultant high mortality depending on the location of dissection if not aggressively treated. Cocaine users are known to have a higher incidence of aortic dissection. We report here aortic dissection in a patient with cocaine abuse which did not respond to traditional medication regimes used currently in this setting. Worth mentioning is the use of an alpha-2 receptor selective agonist named Dexmedetomidine as a treatment modality to control hypertension in this patient, which is approved only for sedation of intubated and mechanically ventilated patients in the intensive care settings and for sedation during invasive procedures. This paper illustrates the practical beneficial role of Dexmedetomidine in controling blood pressure in the settings of cocaine-induced sympathetic surge when other treatment modalities fail. |
| format | Article |
| id | doaj-art-7d7d2bd0389c43418a334426f1515fed |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-7d7d2bd0389c43418a334426f1515fed2025-02-03T05:43:59ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/174132174132Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel IndicationFahad Javed0Alexandre Miguel Benjo1Kiran Reddy2Muhammad Shoaib Akram3Shahzeb Afsar Khan4Manpreet Singh Sabharwal5Girish Nadkarni6Emad F. Aziz7Eyal Herzog8Division of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USADivision of Cardiology, St. Luke's Roosevelt Hospital Center, University Hospital for College of Physicians and Surgeons of Columbia University, 1090 Amsterdam Avenue, New York, NY 10025, USAAortic dissection is a potentially fatal but rare disease characterized by an aortic intimal tear with blood passing into the media creating a false lumen and with resultant high mortality depending on the location of dissection if not aggressively treated. Cocaine users are known to have a higher incidence of aortic dissection. We report here aortic dissection in a patient with cocaine abuse which did not respond to traditional medication regimes used currently in this setting. Worth mentioning is the use of an alpha-2 receptor selective agonist named Dexmedetomidine as a treatment modality to control hypertension in this patient, which is approved only for sedation of intubated and mechanically ventilated patients in the intensive care settings and for sedation during invasive procedures. This paper illustrates the practical beneficial role of Dexmedetomidine in controling blood pressure in the settings of cocaine-induced sympathetic surge when other treatment modalities fail.http://dx.doi.org/10.1155/2011/174132 |
| spellingShingle | Fahad Javed Alexandre Miguel Benjo Kiran Reddy Muhammad Shoaib Akram Shahzeb Afsar Khan Manpreet Singh Sabharwal Girish Nadkarni Emad F. Aziz Eyal Herzog Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication Case Reports in Medicine |
| title | Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication |
| title_full | Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication |
| title_fullStr | Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication |
| title_full_unstemmed | Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication |
| title_short | Dexmedetomidine Use in the Setting of Cocaine-Induced Hypertensive Emergency and Aortic Dissection: A Novel Indication |
| title_sort | dexmedetomidine use in the setting of cocaine induced hypertensive emergency and aortic dissection a novel indication |
| url | http://dx.doi.org/10.1155/2011/174132 |
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