A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma
Neuroendocrine carcinomas (NECs) are malignancies most often found in the colon, lung, pancreas, or thyroid. We describe a rare case of an NEC found in the anal canal of a 68-year-old woman. We also explore a list of differential diagnoses that should be considered in a patient presenting with a rec...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-04-01
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| Series: | World Journal of Colorectal Surgery |
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| Online Access: | https://journals.lww.com/10.4103/WJCS.WJCS_26_19 |
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| author | Michael Gates Nirali Shah Imran Saeed |
| author_facet | Michael Gates Nirali Shah Imran Saeed |
| author_sort | Michael Gates |
| collection | DOAJ |
| description | Neuroendocrine carcinomas (NECs) are malignancies most often found in the colon, lung, pancreas, or thyroid. We describe a rare case of an NEC found in the anal canal of a 68-year-old woman. We also explore a list of differential diagnoses that should be considered in a patient presenting with a rectal mass. Pathological slides with staining for chromogranin, synaptophysin and CDX2 confirm the diagnosis. We are hopeful that this patient is responsive to neoadjuvant chemotherapy and radiation as to allow for a sphincter preserving surgery to ultimately lead to a better quality of life. |
| format | Article |
| id | doaj-art-7d5d77fefabf4e54bf05c3ffdfd76367 |
| institution | OA Journals |
| issn | 1941-8213 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | World Journal of Colorectal Surgery |
| spelling | doaj-art-7d5d77fefabf4e54bf05c3ffdfd763672025-08-20T02:19:22ZengWolters Kluwer Medknow PublicationsWorld Journal of Colorectal Surgery1941-82132020-04-0192283110.4103/WJCS.WJCS_26_19A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine CarcinomaMichael GatesNirali ShahImran SaeedNeuroendocrine carcinomas (NECs) are malignancies most often found in the colon, lung, pancreas, or thyroid. We describe a rare case of an NEC found in the anal canal of a 68-year-old woman. We also explore a list of differential diagnoses that should be considered in a patient presenting with a rectal mass. Pathological slides with staining for chromogranin, synaptophysin and CDX2 confirm the diagnosis. We are hopeful that this patient is responsive to neoadjuvant chemotherapy and radiation as to allow for a sphincter preserving surgery to ultimately lead to a better quality of life.https://journals.lww.com/10.4103/WJCS.WJCS_26_19anal cancerdifferential diagnosis for rectal massnecnetneuroendocrine carcinoma anal canalneuroendocrine tumor |
| spellingShingle | Michael Gates Nirali Shah Imran Saeed A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma World Journal of Colorectal Surgery anal cancer differential diagnosis for rectal mass nec net neuroendocrine carcinoma anal canal neuroendocrine tumor |
| title | A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma |
| title_full | A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma |
| title_fullStr | A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma |
| title_full_unstemmed | A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma |
| title_short | A Mass in the Anal Canal Found to be Poorly Differentiated Small-Cell Neuroendocrine Carcinoma |
| title_sort | mass in the anal canal found to be poorly differentiated small cell neuroendocrine carcinoma |
| topic | anal cancer differential diagnosis for rectal mass nec net neuroendocrine carcinoma anal canal neuroendocrine tumor |
| url | https://journals.lww.com/10.4103/WJCS.WJCS_26_19 |
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