A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus

Although many mathematical models have been presented for glucose and insulin interaction, none of these models can describe diabetes disease completely. In this work, the dynamical behavior of a regulatory system of glucose-insulin incorporating time delay is studied and a new property of the prese...

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Main Authors: Payam Sadeghi Shabestari, Karthikeyan Rajagopal, Bahareh Safarbali, Sajad Jafari, Prakash Duraisamy
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2018/6815190
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author Payam Sadeghi Shabestari
Karthikeyan Rajagopal
Bahareh Safarbali
Sajad Jafari
Prakash Duraisamy
author_facet Payam Sadeghi Shabestari
Karthikeyan Rajagopal
Bahareh Safarbali
Sajad Jafari
Prakash Duraisamy
author_sort Payam Sadeghi Shabestari
collection DOAJ
description Although many mathematical models have been presented for glucose and insulin interaction, none of these models can describe diabetes disease completely. In this work, the dynamical behavior of a regulatory system of glucose-insulin incorporating time delay is studied and a new property of the presented model is revealed. This property can describe the diabetes disease better and therefore may help us in deeper understanding of diabetes, interactions between glucose and insulin, and possible cures for this widespread disease.
format Article
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institution Kabale University
issn 1076-2787
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language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Complexity
spelling doaj-art-7d2b31af58214d39a33de5d4b5acc7ce2025-02-03T01:11:08ZengWileyComplexity1076-27871099-05262018-01-01201810.1155/2018/68151906815190A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes MellitusPayam Sadeghi Shabestari0Karthikeyan Rajagopal1Bahareh Safarbali2Sajad Jafari3Prakash Duraisamy4Biomedical Engineering Department, Amirkabir University of Technology, Tehran 15875-4413, IranDepartment of Electrical and Communication Engineering, The PNG University of Technology, Lae, Papua New GuineaBiomedical Engineering Department, Amirkabir University of Technology, Tehran 15875-4413, IranBiomedical Engineering Department, Amirkabir University of Technology, Tehran 15875-4413, IranCentre for Non-Linear Dynamics, Defense University, Bishoftu, EthiopiaAlthough many mathematical models have been presented for glucose and insulin interaction, none of these models can describe diabetes disease completely. In this work, the dynamical behavior of a regulatory system of glucose-insulin incorporating time delay is studied and a new property of the presented model is revealed. This property can describe the diabetes disease better and therefore may help us in deeper understanding of diabetes, interactions between glucose and insulin, and possible cures for this widespread disease.http://dx.doi.org/10.1155/2018/6815190
spellingShingle Payam Sadeghi Shabestari
Karthikeyan Rajagopal
Bahareh Safarbali
Sajad Jafari
Prakash Duraisamy
A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus
Complexity
title A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus
title_full A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus
title_fullStr A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus
title_full_unstemmed A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus
title_short A Novel Approach to Numerical Modeling of Metabolic System: Investigation of Chaotic Behavior in Diabetes Mellitus
title_sort novel approach to numerical modeling of metabolic system investigation of chaotic behavior in diabetes mellitus
url http://dx.doi.org/10.1155/2018/6815190
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