Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?

Prurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area o...

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Main Authors: Caspar Weel Krammer, Rami Mossad Ibrahim
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Dermatological Medicine
Online Access:http://dx.doi.org/10.1155/2018/9186745
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author Caspar Weel Krammer
Rami Mossad Ibrahim
author_facet Caspar Weel Krammer
Rami Mossad Ibrahim
author_sort Caspar Weel Krammer
collection DOAJ
description Prurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area on a base of irradiated skin which was initially suspected as a skin malignancy. The patient had a history of undifferentiated nasopharyngeal cancer with lymph node involvement which was treated by radiochemotherapy thirteen years previously. Histological examination confirmed that it was a case of prurigo nodularis which subsequently evolved at distant sites. This presentation may suggest a case of an isoradiotopic response.
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institution Kabale University
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publisher Wiley
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series Case Reports in Dermatological Medicine
spelling doaj-art-7d26a9cafbd44b2db02156b7dea9ac4a2025-02-03T01:22:32ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712018-01-01201810.1155/2018/91867459186745Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?Caspar Weel Krammer0Rami Mossad Ibrahim1Department of Plastic Surgery, Hospital South West Jutland, Finsensgade 35, 6700 Esbjerg, DenmarkDepartment of Plastic Surgery, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, DenmarkPrurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area on a base of irradiated skin which was initially suspected as a skin malignancy. The patient had a history of undifferentiated nasopharyngeal cancer with lymph node involvement which was treated by radiochemotherapy thirteen years previously. Histological examination confirmed that it was a case of prurigo nodularis which subsequently evolved at distant sites. This presentation may suggest a case of an isoradiotopic response.http://dx.doi.org/10.1155/2018/9186745
spellingShingle Caspar Weel Krammer
Rami Mossad Ibrahim
Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?
Case Reports in Dermatological Medicine
title Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?
title_full Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?
title_fullStr Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?
title_full_unstemmed Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?
title_short Prurigo Nodularis after Radiotherapy: An Isoradiotopic Response?
title_sort prurigo nodularis after radiotherapy an isoradiotopic response
url http://dx.doi.org/10.1155/2018/9186745
work_keys_str_mv AT casparweelkrammer prurigonodularisafterradiotherapyanisoradiotopicresponse
AT ramimossadibrahim prurigonodularisafterradiotherapyanisoradiotopicresponse