Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome

Background. Superior mesenteric artery (SMA) syndrome is a rare cause of upper gastrointestinal obstruction leading to acute kidney injury (AKI). Methods. We report a case of 23-year-old army personnel who presented with persistent vomiting leading to severe hypokalaemia, metabolic alkalosis, and ac...

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Main Authors: Nur Ezzaty Mohammad Kazmin, Lydia Kamaruzaman, Zhiqin Wong, Voon Ken Fong, Rozita Mohd, Ruslinda Mustafar
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2020/8364176
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author Nur Ezzaty Mohammad Kazmin
Lydia Kamaruzaman
Zhiqin Wong
Voon Ken Fong
Rozita Mohd
Ruslinda Mustafar
author_facet Nur Ezzaty Mohammad Kazmin
Lydia Kamaruzaman
Zhiqin Wong
Voon Ken Fong
Rozita Mohd
Ruslinda Mustafar
author_sort Nur Ezzaty Mohammad Kazmin
collection DOAJ
description Background. Superior mesenteric artery (SMA) syndrome is a rare cause of upper gastrointestinal obstruction leading to acute kidney injury (AKI). Methods. We report a case of 23-year-old army personnel who presented with persistent vomiting leading to severe hypokalaemia, metabolic alkalosis, and acute kidney injury resulting in cardiorespiratory arrest. Results. After successful resuscitation, he was supported with haemodialysis and aggressive electrolytes correction. He was repeatedly not able to tolerate nasogastric (NG) tube feeding and computerised tomography of abdomen was performed, and the diagnosis of SMA syndrome was made. Gastroscopy examination revealed duodenal ulcer at D1, pinhole D1-D2 junction, but there was no evidence of intraluminal mass or lesions leading to upper gastrointestinal obstruction. A nasojejunal tube was inserted to bypass the narrow segment of the duodenum, and he was put on nutritional support. He was subsequently weaned off dialysis support as his renal function gradually improved and later on normalised. He remains symptoms free, and he gained five kilograms in four months after discharge. Conclusions. SMA syndrome is a rare cause of upper gastrointestinal obstruction but should be considered as a differential diagnosis in a patient who presented with recurrent vomiting and AKI with metabolic alkalosis.
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spelling doaj-art-7cfd83d7677047709c5e2be99741b7f92025-02-03T05:51:45ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/83641768364176Acute Kidney Injury Caused by Superior Mesenteric Artery SyndromeNur Ezzaty Mohammad Kazmin0Lydia Kamaruzaman1Zhiqin Wong2Voon Ken Fong3Rozita Mohd4Ruslinda Mustafar5Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, MalaysiaNephrology Unit, Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, MalaysiaGastroenterology Unit, Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, MalaysiaNephrology Unit, Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, MalaysiaNephrology Unit, Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, MalaysiaNephrology Unit, Medical Department, National University of Malaysia Medical Centre, Kuala Lumpur, MalaysiaBackground. Superior mesenteric artery (SMA) syndrome is a rare cause of upper gastrointestinal obstruction leading to acute kidney injury (AKI). Methods. We report a case of 23-year-old army personnel who presented with persistent vomiting leading to severe hypokalaemia, metabolic alkalosis, and acute kidney injury resulting in cardiorespiratory arrest. Results. After successful resuscitation, he was supported with haemodialysis and aggressive electrolytes correction. He was repeatedly not able to tolerate nasogastric (NG) tube feeding and computerised tomography of abdomen was performed, and the diagnosis of SMA syndrome was made. Gastroscopy examination revealed duodenal ulcer at D1, pinhole D1-D2 junction, but there was no evidence of intraluminal mass or lesions leading to upper gastrointestinal obstruction. A nasojejunal tube was inserted to bypass the narrow segment of the duodenum, and he was put on nutritional support. He was subsequently weaned off dialysis support as his renal function gradually improved and later on normalised. He remains symptoms free, and he gained five kilograms in four months after discharge. Conclusions. SMA syndrome is a rare cause of upper gastrointestinal obstruction but should be considered as a differential diagnosis in a patient who presented with recurrent vomiting and AKI with metabolic alkalosis.http://dx.doi.org/10.1155/2020/8364176
spellingShingle Nur Ezzaty Mohammad Kazmin
Lydia Kamaruzaman
Zhiqin Wong
Voon Ken Fong
Rozita Mohd
Ruslinda Mustafar
Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome
Case Reports in Nephrology
title Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome
title_full Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome
title_fullStr Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome
title_full_unstemmed Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome
title_short Acute Kidney Injury Caused by Superior Mesenteric Artery Syndrome
title_sort acute kidney injury caused by superior mesenteric artery syndrome
url http://dx.doi.org/10.1155/2020/8364176
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