Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework

Introduction Digital adherence technologies (DATs) may enable person-centred tuberculosis (TB) treatment monitoring; however, implementation challenges may undermine their effectiveness. Using the reach, effectiveness, adoption, implementation and maintenance framework, we conducted a scoping review...

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Main Authors: Ramnath Subbaraman, Katherine L Fielding, Genevieve Gore, Nicola Foster, Kevin Schwartzman, Miranda Zary, Cedric Kafie, Shruti Bahukudumbi, Chimweta I Chilala, Barbie Patel, Mona S Mohamed
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:BMJ Global Health
Online Access:https://gh.bmj.com/content/10/2/e016608.full
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author Ramnath Subbaraman
Katherine L Fielding
Genevieve Gore
Nicola Foster
Kevin Schwartzman
Miranda Zary
Cedric Kafie
Shruti Bahukudumbi
Chimweta I Chilala
Barbie Patel
Mona S Mohamed
author_facet Ramnath Subbaraman
Katherine L Fielding
Genevieve Gore
Nicola Foster
Kevin Schwartzman
Miranda Zary
Cedric Kafie
Shruti Bahukudumbi
Chimweta I Chilala
Barbie Patel
Mona S Mohamed
author_sort Ramnath Subbaraman
collection DOAJ
description Introduction Digital adherence technologies (DATs) may enable person-centred tuberculosis (TB) treatment monitoring; however, implementation challenges may undermine their effectiveness. Using the reach, effectiveness, adoption, implementation and maintenance framework, we conducted a scoping review to identify contextual factors informing ‘reach’ (DAT engagement by people with TB) and ‘adoption’ (DAT uptake by healthcare providers or clinics).Methods We searched eight databases from 1 January 2000 to 25 April 2023 to identify all TB DAT studies. After extracting qualitative and quantitative findings, using thematic synthesis, we analysed common findings to create meta-themes informing DAT reach or adoption. Meta-themes were further organised using the Unified Theory of Acceptance and Use of Technology, which posits technology use is influenced by perceived usefulness, ease of use, social influences and facilitating conditions.Results 66 reports met inclusion criteria, with 61 reporting on DAT reach among people with TB and 27 reporting on DAT adoption by healthcare providers. Meta-themes promoting reach included perceptions that DATs improved medication adherence, facilitated communication with providers, made people feel more ‘cared for’ and enhanced convenience compared with alternative care models (perceived usefulness) and lowered stigma (social influences). Meta-themes limiting reach included literacy and language barriers and DAT technical complexity (ease of use); increased stigma (social influences) and suboptimal DAT function and complex cellular accessibility challenges (facilitating conditions). Meta-themes promoting adoption included perceptions that DATs improved care quality or efficiency (perceived usefulness). Meta-themes limiting adoption included negative DAT impacts on workload or employment and suboptimal accuracy of adherence data (perceived usefulness); and suboptimal DAT function, complex cellular accessibility challenges and insufficient provider training (facilitating conditions). Limitations of this review include the limited studies informing adoption meta-themes.Conclusion This review identifies diverse contextual factors that can inform improvements in DAT design and implementation to achieve higher engagement by people with TB and healthcare providers, which could improve intervention effectiveness.
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spelling doaj-art-7cd53ffe4d2f4cc8b0c73cf595d986212025-08-20T03:12:42ZengBMJ Publishing GroupBMJ Global Health2059-79082025-02-0110210.1136/bmjgh-2024-016608Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM frameworkRamnath Subbaraman0Katherine L Fielding1Genevieve Gore2Nicola Foster3Kevin Schwartzman4Miranda Zary5Cedric Kafie6Shruti Bahukudumbi7Chimweta I Chilala8Barbie Patel9Mona S Mohamed10Division of Geographic Medicine and Infectious Diseases, Tufts Medical Center, Boston, Massachusetts, USATB Centre, London School of Hygiene and Tropical Medicine, London, UKSchulich Library of Physical Sciences, Life Sciences, and Engineering, McGill University, Montreal, Quebec, CanadaTB Centre, London School of Hygiene and Tropical Medicine, London, UKMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, CanadaMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, CanadaMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, CanadaDepartment of Public Health and Community Medicine and Center for Global Public Health, Tufts University School of Medicine, Boston, Massachusetts, USATB Centre, London School of Hygiene and Tropical Medicine, London, UKDepartment of Public Health and Community Medicine and Center for Global Public Health, Tufts University School of Medicine, Boston, Massachusetts, USAMcGill International Tuberculosis Centre, Research Institute of the McGill University Health Centre, Montreal, Quebec, CanadaIntroduction Digital adherence technologies (DATs) may enable person-centred tuberculosis (TB) treatment monitoring; however, implementation challenges may undermine their effectiveness. Using the reach, effectiveness, adoption, implementation and maintenance framework, we conducted a scoping review to identify contextual factors informing ‘reach’ (DAT engagement by people with TB) and ‘adoption’ (DAT uptake by healthcare providers or clinics).Methods We searched eight databases from 1 January 2000 to 25 April 2023 to identify all TB DAT studies. After extracting qualitative and quantitative findings, using thematic synthesis, we analysed common findings to create meta-themes informing DAT reach or adoption. Meta-themes were further organised using the Unified Theory of Acceptance and Use of Technology, which posits technology use is influenced by perceived usefulness, ease of use, social influences and facilitating conditions.Results 66 reports met inclusion criteria, with 61 reporting on DAT reach among people with TB and 27 reporting on DAT adoption by healthcare providers. Meta-themes promoting reach included perceptions that DATs improved medication adherence, facilitated communication with providers, made people feel more ‘cared for’ and enhanced convenience compared with alternative care models (perceived usefulness) and lowered stigma (social influences). Meta-themes limiting reach included literacy and language barriers and DAT technical complexity (ease of use); increased stigma (social influences) and suboptimal DAT function and complex cellular accessibility challenges (facilitating conditions). Meta-themes promoting adoption included perceptions that DATs improved care quality or efficiency (perceived usefulness). Meta-themes limiting adoption included negative DAT impacts on workload or employment and suboptimal accuracy of adherence data (perceived usefulness); and suboptimal DAT function, complex cellular accessibility challenges and insufficient provider training (facilitating conditions). Limitations of this review include the limited studies informing adoption meta-themes.Conclusion This review identifies diverse contextual factors that can inform improvements in DAT design and implementation to achieve higher engagement by people with TB and healthcare providers, which could improve intervention effectiveness.https://gh.bmj.com/content/10/2/e016608.full
spellingShingle Ramnath Subbaraman
Katherine L Fielding
Genevieve Gore
Nicola Foster
Kevin Schwartzman
Miranda Zary
Cedric Kafie
Shruti Bahukudumbi
Chimweta I Chilala
Barbie Patel
Mona S Mohamed
Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework
BMJ Global Health
title Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework
title_full Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework
title_fullStr Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework
title_full_unstemmed Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework
title_short Contextual factors influencing implementation of tuberculosis digital adherence technologies: a scoping review guided by the RE-AIM framework
title_sort contextual factors influencing implementation of tuberculosis digital adherence technologies a scoping review guided by the re aim framework
url https://gh.bmj.com/content/10/2/e016608.full
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