Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction

Human parvovirus B19 (PVB19) infection causes neurological manifestations, including encephalitis, meningitis, and neuropathy, but facial nerve palsy is rare. Moreover, no case of facial nerve palsy related to PVB19 infection that was diagnosed by PCR and serology has been reported. A 19-month-old b...

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Main Authors: Taro Fukuta, Yoshihiko Kawano, Maiko Ikeda, Jun-ichi Kawada, Yoshinori Ito, Shinya Hara
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2022/4574640
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author Taro Fukuta
Yoshihiko Kawano
Maiko Ikeda
Jun-ichi Kawada
Yoshinori Ito
Shinya Hara
author_facet Taro Fukuta
Yoshihiko Kawano
Maiko Ikeda
Jun-ichi Kawada
Yoshinori Ito
Shinya Hara
author_sort Taro Fukuta
collection DOAJ
description Human parvovirus B19 (PVB19) infection causes neurological manifestations, including encephalitis, meningitis, and neuropathy, but facial nerve palsy is rare. Moreover, no case of facial nerve palsy related to PVB19 infection that was diagnosed by PCR and serology has been reported. A 19-month-old boy without the medical history developed facial nerve palsy and was treated with prednisolone and valacyclovir. On the 19th day, erythema appeared on his body, and the PVB19-specific IgM and PVB19 DNA were detected in the serum, leading to the diagnosis of infectious erythema associated with PVB19 infection. This case indicates that PVB19 may be one of the causative agents of facial nerve palsy.
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institution Kabale University
issn 2090-6811
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publishDate 2022-01-01
publisher Wiley
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series Case Reports in Pediatrics
spelling doaj-art-7cbd234738a541d2b3ce70cc0aaa40702025-02-03T05:59:11ZengWileyCase Reports in Pediatrics2090-68112022-01-01202210.1155/2022/4574640Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain ReactionTaro Fukuta0Yoshihiko Kawano1Maiko Ikeda2Jun-ichi Kawada3Yoshinori Ito4Shinya Hara5Department of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsHuman parvovirus B19 (PVB19) infection causes neurological manifestations, including encephalitis, meningitis, and neuropathy, but facial nerve palsy is rare. Moreover, no case of facial nerve palsy related to PVB19 infection that was diagnosed by PCR and serology has been reported. A 19-month-old boy without the medical history developed facial nerve palsy and was treated with prednisolone and valacyclovir. On the 19th day, erythema appeared on his body, and the PVB19-specific IgM and PVB19 DNA were detected in the serum, leading to the diagnosis of infectious erythema associated with PVB19 infection. This case indicates that PVB19 may be one of the causative agents of facial nerve palsy.http://dx.doi.org/10.1155/2022/4574640
spellingShingle Taro Fukuta
Yoshihiko Kawano
Maiko Ikeda
Jun-ichi Kawada
Yoshinori Ito
Shinya Hara
Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction
Case Reports in Pediatrics
title Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction
title_full Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction
title_fullStr Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction
title_full_unstemmed Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction
title_short Diagnosis of Peripheral Facial Palsy Associated with Parvovirus B19 Infection by Polymerase Chain Reaction
title_sort diagnosis of peripheral facial palsy associated with parvovirus b19 infection by polymerase chain reaction
url http://dx.doi.org/10.1155/2022/4574640
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