Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-κB Signaling

Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-κB Signaling

Homoharringtonine (HHT) exhibits an anti-inflammatory activity. The potential protective effects and mechanisms of HHT on dextran sulfate sodium- (DSS-) induced colitis were investigated. DSS-induced colitis mice were intraperitoneally injected with HHT. Body weight, colon length, disease activity i...

Full description

Saved in:

Bibliographic Details
Main Authors:	Jiangrui Liu, Liangpan Shi, Wenchang Huang, Zhihua Zheng, Xiaohui Huang, Yibin Su
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Mediators of Inflammation
Online Access:	http://dx.doi.org/10.1155/2022/3441357
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Boehmeria nivea Attenuates the Development of Dextran Sulfate Sodium-Induced Experimental Colitis
by: Eun Ju Shin, et al.
Published: (2014-01-01)

A Picrorhiza kurroa Derivative, Picroliv, Attenuates the Development of Dextran-Sulfate-Sodium-Induced Colitis in Mice
by: De-Kui Zhang, et al.
Published: (2012-01-01)

Protective Effect of Daikenchuto on Dextran Sulfate Sodium-Induced Colitis in Mice
by: Takaharu Matsunaga, et al.
Published: (2017-01-01)

5-Methoxytryptophan Alleviates Dextran Sulfate Sodium-Induced Colitis by Inhibiting the Intestinal Epithelial Damage and Inflammatory Response
by: Yanling Wang, et al.
Published: (2024-01-01)

Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
by: Yizhuo Wang, et al.
Published: (2021-01-01)

Dextran sodium sulfate-induced colitis alters the proportion and composition of replicating gut bacteria
by: Eve T. Beauchemin, et al.
Published: (2025-01-01)

Formononetin Administration Ameliorates Dextran Sulfate Sodium-Induced Acute Colitis by Inhibiting NLRP3 Inflammasome Signaling Pathway
by: Dacheng Wu, et al.
Published: (2018-01-01)

Donkey whey proteins ameliorate dextran sulfate sodium-induced ulcerative colitis in mice by downregulating the S100A8-TRAF6-NF-κB axis-mediated inflammatory response
by: Mohan Li, et al.
Published: (2023-09-01)

Studies on the alleviating effect of Bifidobacterium lactis V9 on dextran sodium sulfate-induced colitis in mice
by: Xiaoyan Duan, et al.
Published: (2025-01-01)

Xi Lei San Attenuates Dextran Sulfate Sodium-Induced Colitis in Rats and TNF-α-Stimulated Colitis in CACO2 Cells: Involvement of the NLRP3 Inflammasome and Autophagy
by: Zhang Tao, et al.
Published: (2021-01-01)

EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats
by: Xue Bing, et al.
Published: (2017-01-01)

The protective effect of carnosic acid on dextran sulfate sodium-induced colitis based on metabolomics and gut microbiota analysis
by: Changhui Du, et al.
Published: (2023-07-01)

Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides
by: Bing Wei, et al.
Published: (2018-01-01)

Chick Early Amniotic Fluid Alleviates Dextran-Sulfate-Sodium-Induced Colitis in Mice via T-Cell Receptor Pathway
by: Fan Chen, et al.
Published: (2025-01-01)

Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters
by: Kit-Leong Cheong, et al.
Published: (2025-03-01)

Nicotinamide Ameliorates Dextran Sulfate Sodium-Induced Chronic Colitis in Mice through Its Anti-Inflammatory Properties and Modulates the Gut Microbiota
by: Kai Kang, et al.
Published: (2021-01-01)

Lunasin protease inhibitor concentrate decreases pro-inflammatory cytokines and improves histopathological markers in dextran sodium sulfate-induced ulcerative colitis
by: Andrea Nieto-Veloza, et al.
Published: (2022-11-01)

D-Psicose intake exacerbates dextran sulfate sodium-induced colitis in mice through alteration in the gut microbiota and dysfunction of mucosal barrier
by: Xuejiao Zhang, et al.
Published: (2024-01-01)

In Vitro Antioxidant, Anti-inflammatory, and In Vivo Anticolitis Effects of Combretin A and Combretin B on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
by: Mbiantcha Marius, et al.
Published: (2020-01-01)

Homoharringtonine: mechanisms, clinical applications and research progress
by: Wen Wang, et al.
Published: (2025-01-01)

Probiotic administration aggravates dextran sulfate sodium salt-induced inflammation and intestinal epithelium disruption in weaned pig
by: Kunhong Xie, et al.
Published: (2025-01-01)

Melatonin Reduces Inflammatory Injury Through Inhibiting NF-κB Activation in Rats With Colitis
by: Jun-Hua Li, et al.
Published: (2005-01-01)

Protective Effect of Amphipterygium adstringens Extract on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice
by: Mario Rodriguez-Canales, et al.
Published: (2016-01-01)

Acer palmatum thumb. Ethanol Extract Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation
by: Kwang-Youn Kim, et al.
Published: (2018-01-01)

Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis
by: Fanxuan Zhang, et al.
Published: (2025-01-01)

Effects of repeated intragastric administrations with heat-inactivated Mycobacterium aurum DSM 33539 on the stress-induced aggravation of dextran sulfate sodium (DSS) colitis in C57BL/6N mice
by: Dominik Langgartner, et al.
Published: (2025-01-01)

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway
by: Liwei Wu, et al.
Published: (2017-01-01)

Phillyrin ameliorates DSS-induced colitis in mice via modulating the gut microbiota and inhibiting the NF-κB/MLCK pathway
by: Tong Li, et al.
Published: (2025-02-01)

Corrosion Inhibition of Mild Steel in Hydrochloric Acid by Sodium Lauryl Sulfate (SLS)
by: Atul Kumar
Published: (2008-01-01)

Rapamycin Alleviates 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis through Autophagy Induction and NF-κB Pathway Inhibition in Mice
by: Zhen Ni, et al.
Published: (2022-01-01)

A Novel, Cell-Compatible Hyaluronidase Activity Assay Identifies Dextran Sulfates and Other Sulfated Polymeric Hydrocarbons as Potent Inhibitors for CEMIP
by: Anja Schmaus, et al.
Published: (2025-01-01)

Sulforaphane attenuates dextran sodium sulphate induced intestinal inflammation via IL-10/STAT3 signaling mediated macrophage phenotype switching
by: Yuyang Sun, et al.
Published: (2022-01-01)

Paeonol Attenuates Methotrexate-Induced Cardiac Toxicity in Rats by Inhibiting Oxidative Stress and Suppressing TLR4-Induced NF-κB Inflammatory Pathway
by: Abdulla Y. Al-Taher, et al.
Published: (2020-01-01)

The role of NF-κB in diabetic cardiomyopathy
by: Huang-Jun Liu, et al.
Published: (2024-12-01)

Influence of Rosiglitazone on the Expression of PPARγ, NF-κB, and TNF-α in Rat Model of Ulcerative Colitis
by: Jing-Wei Mao, et al.
Published: (2012-01-01)

Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways
by: Liang Zhu, et al.
Published: (2025-02-01)

Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways
by: Jing Huang, et al.
Published: (2025-01-01)

METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway
by: Jinghua Wang, et al.
Published: (2019-01-01)

Modified Gegen Qinlian Decoction Ameliorates DSS-Induced Colitis in Mice via the Modulation of NF-κB and Nrf2/HO-1 Pathways
by: Jinke Huang, et al.
Published: (2025-01-01)

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice
by: Wei-Jian Zhang, et al.
Published: (2015-01-01)