Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels

Role of nitric oxide synthase on brain GABA transaminase activity and GABA levels

In an attempt to clarify the controversial role of nitric oxide (NO) in seizures, the effects of NO on brain GABA transaminase (GABA-T) activity and GABA levels were investigated. To this aim, the effects of the substrate (l-arginine) and inhibitors (Nω-nitro-l-arginine methyl ester, 7-nitroindazole...

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Bibliographic Details
Main Authors: Vega Rasgado Lourdes A., Reyes Guillermo Ceballos, Vega Díaz Fernando
Format: Article
Language:English
Published: Sciendo 2018-09-01
Series:Acta Pharmaceutica
Subjects:
nitric oxide
gaba-transaminase
gaba
seizures
Online Access:https://doi.org/10.2478/acph-2018-0022
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