Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review
Toxicological emergencies pose a significant health burden in Nepal, particularly in rural agricultural regions. Intentional pesticide self-poisoning, especially with organophosphates, contribute heavily to this burden. This narrative review synthesizes the current state of toxicological care in Nep...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Toxicology Communications |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/24734306.2025.2452670 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832585002460643328 |
|---|---|
| author | Rakesh Ghimire Rajesh Sharma Sangha Ratna Bajracharya Manish Yadav Ziad Kazzi Bibhav Acharya Michael Eddleston Ramu Kharel |
| author_facet | Rakesh Ghimire Rajesh Sharma Sangha Ratna Bajracharya Manish Yadav Ziad Kazzi Bibhav Acharya Michael Eddleston Ramu Kharel |
| author_sort | Rakesh Ghimire |
| collection | DOAJ |
| description | Toxicological emergencies pose a significant health burden in Nepal, particularly in rural agricultural regions. Intentional pesticide self-poisoning, especially with organophosphates, contribute heavily to this burden. This narrative review synthesizes the current state of toxicological care in Nepal, highlighting epidemiological data, educational programs, policy developments, and resource availability up to 2024. Despite hospital-based studies, aggregate data on toxicology care is lacking. Major barriers include insufficient trained human resources and limited access to antidotes and antivenoms. The review emphasizes the urgent need for formal clinical toxicology training, improved toxicological emergency management, and policy implementation to reduce the burden of poisoning in Nepal. |
| format | Article |
| id | doaj-art-7c6eab59390f4e2cae36fb04883576db |
| institution | Kabale University |
| issn | 2473-4306 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Toxicology Communications |
| spelling | doaj-art-7c6eab59390f4e2cae36fb04883576db2025-01-27T06:49:27ZengTaylor & Francis GroupToxicology Communications2473-43062025-12-019110.1080/24734306.2025.2452670Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative reviewRakesh Ghimire0Rajesh Sharma1Sangha Ratna Bajracharya2Manish Yadav3Ziad Kazzi4Bibhav Acharya5Michael Eddleston6Ramu Kharel7Maharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, NepalDrug and Toxicology Center, Poison Information Center, Tribhuvan University Teaching Hospital, NepalMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, NepalMaharajgunj Medical Campus, Institute of Medicine, Tribhuvan University, NepalDepartment of Emergency Medicine, Emory University School of Medicine, USADepartment of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, USACentre for Pesticide Suicide Prevention, University of Edinburgh, Edinburgh, United KingdomDepartment of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI, USAToxicological emergencies pose a significant health burden in Nepal, particularly in rural agricultural regions. Intentional pesticide self-poisoning, especially with organophosphates, contribute heavily to this burden. This narrative review synthesizes the current state of toxicological care in Nepal, highlighting epidemiological data, educational programs, policy developments, and resource availability up to 2024. Despite hospital-based studies, aggregate data on toxicology care is lacking. Major barriers include insufficient trained human resources and limited access to antidotes and antivenoms. The review emphasizes the urgent need for formal clinical toxicology training, improved toxicological emergency management, and policy implementation to reduce the burden of poisoning in Nepal.https://www.tandfonline.com/doi/10.1080/24734306.2025.2452670Nepalemergency carepesticide poisoningclinical toxicologysnakebite |
| spellingShingle | Rakesh Ghimire Rajesh Sharma Sangha Ratna Bajracharya Manish Yadav Ziad Kazzi Bibhav Acharya Michael Eddleston Ramu Kharel Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review Toxicology Communications Nepal emergency care pesticide poisoning clinical toxicology snakebite |
| title | Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review |
| title_full | Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review |
| title_fullStr | Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review |
| title_full_unstemmed | Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review |
| title_short | Challenges, progress, and opportunities in clinical toxicology in Nepal: a narrative review |
| title_sort | challenges progress and opportunities in clinical toxicology in nepal a narrative review |
| topic | Nepal emergency care pesticide poisoning clinical toxicology snakebite |
| url | https://www.tandfonline.com/doi/10.1080/24734306.2025.2452670 |
| work_keys_str_mv | AT rakeshghimire challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT rajeshsharma challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT sangharatnabajracharya challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT manishyadav challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT ziadkazzi challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT bibhavacharya challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT michaeleddleston challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview AT ramukharel challengesprogressandopportunitiesinclinicaltoxicologyinnepalanarrativereview |