Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application

Abstract. Functional gastrointestinal disorders (FGIDs) are debilitating diseases of the digestive system that severely impair an individual’s quality of life and impose a significant economic burden. However, the mechanisms underlying the pathogenesis of FGIDs and effective treatment options remain...

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Main Authors: Mingyao Weng, Jiayue Wang, Yiran Liu, Shuangling Ou, Jinyi Xiang, Guanting Huang, Jingnan Xiong, Qiuyan Wu, Yuhan Zhou, Hao Zhou, Dan Wang
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2024-12-01
Series:Science of Traditional Chinese Medicine
Online Access:http://journals.lww.com/10.1097/st9.0000000000000051
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author Mingyao Weng
Jiayue Wang
Yiran Liu
Shuangling Ou
Jinyi Xiang
Guanting Huang
Jingnan Xiong
Qiuyan Wu
Yuhan Zhou
Hao Zhou
Dan Wang
author_facet Mingyao Weng
Jiayue Wang
Yiran Liu
Shuangling Ou
Jinyi Xiang
Guanting Huang
Jingnan Xiong
Qiuyan Wu
Yuhan Zhou
Hao Zhou
Dan Wang
author_sort Mingyao Weng
collection DOAJ
description Abstract. Functional gastrointestinal disorders (FGIDs) are debilitating diseases of the digestive system that severely impair an individual’s quality of life and impose a significant economic burden. However, the mechanisms underlying the pathogenesis of FGIDs and effective treatment options remain unclear. Transcutaneous auricular vagus nerve stimulation (taVNS), a novel neuromodulation therapy, has shown promising therapeutic outcomes in the treatment of FGIDs. This study conducted a comprehensive analysis of the development of taVNS and its relationship with vagus nerve stimulation and explored the clinical application of taVNS in managing FGIDs, including functional dyspepsia, irritable bowel syndrome, and functional constipation. Additionally, this study investigated the pathophysiological mechanisms of taVNS in FGIDs and reviewed its application as a holistic treatment approach, aiming to provide new insights into its therapeutic potential.
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institution OA Journals
issn 2836-922X
2836-9211
language English
publishDate 2024-12-01
publisher Wolters Kluwer Health/LWW
record_format Article
series Science of Traditional Chinese Medicine
spelling doaj-art-7c5f2f00a73b4cb8af2f5dfc139113e72025-08-20T02:26:10ZengWolters Kluwer Health/LWWScience of Traditional Chinese Medicine2836-922X2836-92112024-12-012427628310.1097/st9.0000000000000051202412000-00003Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to applicationMingyao Weng0Jiayue Wang1Yiran Liu2Shuangling Ou3Jinyi Xiang4Guanting Huang5Jingnan Xiong6Qiuyan Wu7Yuhan Zhou8Hao Zhou9Dan Wang10a College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinaa College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinaa College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinaa College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinaa College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinaa College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinab Second Clinical College, Chongqing Medical University, Chongqing, Chinaa College of Traditional Chinese Medicine, Chongqing Medical University, Chongqing, Chinab Second Clinical College, Chongqing Medical University, Chongqing, Chinac Sichuan Integrative Medicine Hospital Department of TCM Prevention and Health Care, Chengdu, Chinad Department of Acupuncture-Moxibustion and Tuina, Chongqing University of Chinese Medicine, Chongqing, ChinaAbstract. Functional gastrointestinal disorders (FGIDs) are debilitating diseases of the digestive system that severely impair an individual’s quality of life and impose a significant economic burden. However, the mechanisms underlying the pathogenesis of FGIDs and effective treatment options remain unclear. Transcutaneous auricular vagus nerve stimulation (taVNS), a novel neuromodulation therapy, has shown promising therapeutic outcomes in the treatment of FGIDs. This study conducted a comprehensive analysis of the development of taVNS and its relationship with vagus nerve stimulation and explored the clinical application of taVNS in managing FGIDs, including functional dyspepsia, irritable bowel syndrome, and functional constipation. Additionally, this study investigated the pathophysiological mechanisms of taVNS in FGIDs and reviewed its application as a holistic treatment approach, aiming to provide new insights into its therapeutic potential.http://journals.lww.com/10.1097/st9.0000000000000051
spellingShingle Mingyao Weng
Jiayue Wang
Yiran Liu
Shuangling Ou
Jinyi Xiang
Guanting Huang
Jingnan Xiong
Qiuyan Wu
Yuhan Zhou
Hao Zhou
Dan Wang
Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application
Science of Traditional Chinese Medicine
title Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application
title_full Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application
title_fullStr Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application
title_full_unstemmed Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application
title_short Transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders: From understanding to application
title_sort transcutaneous auricular vagus nerve stimulation for functional gastrointestinal disorders from understanding to application
url http://journals.lww.com/10.1097/st9.0000000000000051
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