Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar
Neonatal jaundice is a common disorder worldwide affecting 30-70% of newborn infants. Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries. OBJECTIVES: To determine the frequency of congenital hypothy...
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| Format: | Article |
| Language: | English |
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Rawalpindi Medical University
2023-01-01
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| Series: | Journal of Rawalpindi Medical College |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/1768 |
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| author | Abdul Ahad Romana Bibi Sijad Ur Rehman Majid Ali Shah Matea Ullah Shahinda |
| author_facet | Abdul Ahad Romana Bibi Sijad Ur Rehman Majid Ali Shah Matea Ullah Shahinda |
| author_sort | Abdul Ahad |
| collection | DOAJ |
| description |
Neonatal jaundice is a common disorder worldwide affecting 30-70% of newborn infants. Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries.
OBJECTIVES:
To determine the frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital Peshawar.
METHODOLOGY:
Settings: removed for blind review
Duration: Period of 1 year from January 2020- January 2021.
Study Design: Descriptive (cross sectional) study.
Results:
In our study 489 mothers 386(79%) mothers were in age range 18-30 years while 103(21%) mothers were in age range 31-40 years. 279(57%) babies were male and 210(43%) babies were female. 303(62%) newborns had maternal gestation age ≤38 weeks and 186(38%) neonates had gestation age >38 weeks. 352(72%) newborns had duration of jaundice ≤14 days and 137(28%) newborns had duration of jaundice >14 days. Birth weight was analyzed as 200(41%) newborns had birth weight ≤2.5 kg and 289(59%) newborns had birth weight >2.5 kg. 15(3%) Mothers had positive history of hypothyroidism while 474(97%) mothers had negative history of hypothyroidism . 24(5%) mother had positive history of anti-thyroid drug intake while 465(95%) mothers had negative history of anti-thyroid drug intake. 5(1%) newborn had congenital hypothyroidism while 484(99%) newborn didn’t had congenital hypothyroidism.
Conclusion:
Our study concludes that the frequency of congenital hypothyroidism was 1% in new born admitted with neonatal jaundice at tertiary care hospital Peshawar.
Key words:
Hypothyroidism, Jaundice, kernicterus, bilirubin, morbidity, anti-thyroid drugs.
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| format | Article |
| id | doaj-art-7c5d548dee4d43b0a41e8b8be46c11bd |
| institution | Kabale University |
| issn | 1683-3562 1683-3570 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Rawalpindi Medical University |
| record_format | Article |
| series | Journal of Rawalpindi Medical College |
| spelling | doaj-art-7c5d548dee4d43b0a41e8b8be46c11bd2025-02-06T08:45:18ZengRawalpindi Medical UniversityJournal of Rawalpindi Medical College1683-35621683-35702023-01-0126410.37939/jrmc.v26i4.1768 Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawarAbdul AhadRomana BibiSijad Ur RehmanMajid Ali ShahMatea UllahShahinda Neonatal jaundice is a common disorder worldwide affecting 30-70% of newborn infants. Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries. OBJECTIVES: To determine the frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital Peshawar. METHODOLOGY: Settings: removed for blind review Duration: Period of 1 year from January 2020- January 2021. Study Design: Descriptive (cross sectional) study. Results: In our study 489 mothers 386(79%) mothers were in age range 18-30 years while 103(21%) mothers were in age range 31-40 years. 279(57%) babies were male and 210(43%) babies were female. 303(62%) newborns had maternal gestation age ≤38 weeks and 186(38%) neonates had gestation age >38 weeks. 352(72%) newborns had duration of jaundice ≤14 days and 137(28%) newborns had duration of jaundice >14 days. Birth weight was analyzed as 200(41%) newborns had birth weight ≤2.5 kg and 289(59%) newborns had birth weight >2.5 kg. 15(3%) Mothers had positive history of hypothyroidism while 474(97%) mothers had negative history of hypothyroidism . 24(5%) mother had positive history of anti-thyroid drug intake while 465(95%) mothers had negative history of anti-thyroid drug intake. 5(1%) newborn had congenital hypothyroidism while 484(99%) newborn didn’t had congenital hypothyroidism. Conclusion: Our study concludes that the frequency of congenital hypothyroidism was 1% in new born admitted with neonatal jaundice at tertiary care hospital Peshawar. Key words: Hypothyroidism, Jaundice, kernicterus, bilirubin, morbidity, anti-thyroid drugs. https://www.journalrmc.com/index.php/JRMC/article/view/1768 |
| spellingShingle | Abdul Ahad Romana Bibi Sijad Ur Rehman Majid Ali Shah Matea Ullah Shahinda Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar Journal of Rawalpindi Medical College |
| title | Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar |
| title_full | Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar |
| title_fullStr | Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar |
| title_full_unstemmed | Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar |
| title_short | Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar |
| title_sort | frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar |
| url | https://www.journalrmc.com/index.php/JRMC/article/view/1768 |
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