Frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital peshawar
Neonatal jaundice is a common disorder worldwide affecting 30-70% of newborn infants. Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries. OBJECTIVES: To determine the frequency of congenital hypothy...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Rawalpindi Medical University
2023-01-01
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| Series: | Journal of Rawalpindi Medical College |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/1768 |
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| Summary: | Neonatal jaundice is a common disorder worldwide affecting 30-70% of newborn infants. Severe neonatal jaundice and its progression to kernicterus is a leading cause of death and disability among newborns in poorly-resourced countries.
OBJECTIVES:
To determine the frequency of congenital hypothyroidism in new born admitted with neonatal jaundice at tertiary care hospital Peshawar.
METHODOLOGY:
Settings: removed for blind review
Duration: Period of 1 year from January 2020- January 2021.
Study Design: Descriptive (cross sectional) study.
Results:
In our study 489 mothers 386(79%) mothers were in age range 18-30 years while 103(21%) mothers were in age range 31-40 years. 279(57%) babies were male and 210(43%) babies were female. 303(62%) newborns had maternal gestation age ≤38 weeks and 186(38%) neonates had gestation age >38 weeks. 352(72%) newborns had duration of jaundice ≤14 days and 137(28%) newborns had duration of jaundice >14 days. Birth weight was analyzed as 200(41%) newborns had birth weight ≤2.5 kg and 289(59%) newborns had birth weight >2.5 kg. 15(3%) Mothers had positive history of hypothyroidism while 474(97%) mothers had negative history of hypothyroidism . 24(5%) mother had positive history of anti-thyroid drug intake while 465(95%) mothers had negative history of anti-thyroid drug intake. 5(1%) newborn had congenital hypothyroidism while 484(99%) newborn didn’t had congenital hypothyroidism.
Conclusion:
Our study concludes that the frequency of congenital hypothyroidism was 1% in new born admitted with neonatal jaundice at tertiary care hospital Peshawar.
Key words:
Hypothyroidism, Jaundice, kernicterus, bilirubin, morbidity, anti-thyroid drugs.
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| ISSN: | 1683-3562 1683-3570 |