The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction
ABSTRACT Background After acute myocardial infarction (AMI), it is common to observe new‐onset atrial fibrillation (NOAF), which is often related to a negative prognosis. Some P‐wave variables (P‐wave duration [PWD], P‐wave amplitude, and interatrial block [IAB]), reflecting the process of electrica...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Annals of Noninvasive Electrocardiology |
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| Online Access: | https://doi.org/10.1111/anec.70041 |
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| author | Na Yang Xiaoyan Li Bo Wu Longhao Dai Shaobin Yang Qinning Zhang Shaobin Jia |
| author_facet | Na Yang Xiaoyan Li Bo Wu Longhao Dai Shaobin Yang Qinning Zhang Shaobin Jia |
| author_sort | Na Yang |
| collection | DOAJ |
| description | ABSTRACT Background After acute myocardial infarction (AMI), it is common to observe new‐onset atrial fibrillation (NOAF), which is often related to a negative prognosis. Some P‐wave variables (P‐wave duration [PWD], P‐wave amplitude, and interatrial block [IAB]), reflecting the process of electrical and structural remodeling, could predict the risk of atrial fibrillation (AF). This study aimed to assess the predictive value of P‐wave variables for post‐AMI NOAF. Methods We retrospectively analyzed 1581 AMI patients with no prior AF, using follow‐up data from January 2023 to January 2024. P‐wave variables were measured, and patients were grouped based on in‐hospital NOAF occurrence. Results Overall, 164 (10.3%) of the 1581 patients had NOAF. The age (61.08 ± 12.02 vs. 67.91 ± 11.60, p < 0.001), left atrial size (36.31 ± 3.94 vs. 39.12 ± 5.51, p < 0.001), Brain Natriuretic Peptide (1588.45 ± 3346.18 vs. 3864.39 ± 6251.92, p < 0.001), P‐wave variables (PWD: 102.78 ± 12.56 vs. 117.88 ± 18.81, p < 0.001; P‐wave amplitude: 0.12 ± 0.04 vs. 0.13 ± 0.04, p = 0.041; interatrial block: 89.6% vs. 10.3%, p < 0.001), congestive heart failure (4.7% vs. 23.2%, p < 0.001), and Killip > 1 (25.3% vs. 55.5%, p < 0.001) showed significant differences between the non‐AF and NOAF groups. P‐wave variables were significantly associated with an increased risk of NOAF in multivariable regression analysis. Conclusions The addition of P‐wave variables to AF risk factors from literature and guidelines significantly improved NOAF risk discrimination. P‐wave variables were strongly associated with NOAF after AMI. Adding these variables enhanced the predictive performance for post‐AMI NOAF. |
| format | Article |
| id | doaj-art-7c5681d7d6da427cafe5f6845b4863bc |
| institution | Kabale University |
| issn | 1082-720X 1542-474X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Noninvasive Electrocardiology |
| spelling | doaj-art-7c5681d7d6da427cafe5f6845b4863bc2025-01-28T05:38:41ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2025-01-01301n/an/a10.1111/anec.70041The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial InfarctionNa Yang0Xiaoyan Li1Bo Wu2Longhao Dai3Shaobin Yang4Qinning Zhang5Shaobin Jia6School of Clinical Medicine, Clinical Medicine Ningxia Medical University Yinchuan People's Republic of ChinaResident of Cardiology, Department of Heart Centre Wuzhong People's Hospital Wuzhong People's Republic of ChinaSchool of Clinical Medicine, Clinical Medicine Ningxia Medical University Yinchuan People's Republic of ChinaSchool of Chemical and Biological Engineering Yinchuan University of Energy Yinchuan People's Republic of ChinaHeart Centre General Hospital of Ningxia Medical University Yinchuan People's Republic of ChinaSchool of Clinical Medicine, Clinical Medicine Ningxia Medical University Yinchuan People's Republic of ChinaHeart Centre & Department of Cardiovascular Diseases and Institute of Medical Sciences General Hospital of Ningxia Medical University Yinchuan People's Republic of ChinaABSTRACT Background After acute myocardial infarction (AMI), it is common to observe new‐onset atrial fibrillation (NOAF), which is often related to a negative prognosis. Some P‐wave variables (P‐wave duration [PWD], P‐wave amplitude, and interatrial block [IAB]), reflecting the process of electrical and structural remodeling, could predict the risk of atrial fibrillation (AF). This study aimed to assess the predictive value of P‐wave variables for post‐AMI NOAF. Methods We retrospectively analyzed 1581 AMI patients with no prior AF, using follow‐up data from January 2023 to January 2024. P‐wave variables were measured, and patients were grouped based on in‐hospital NOAF occurrence. Results Overall, 164 (10.3%) of the 1581 patients had NOAF. The age (61.08 ± 12.02 vs. 67.91 ± 11.60, p < 0.001), left atrial size (36.31 ± 3.94 vs. 39.12 ± 5.51, p < 0.001), Brain Natriuretic Peptide (1588.45 ± 3346.18 vs. 3864.39 ± 6251.92, p < 0.001), P‐wave variables (PWD: 102.78 ± 12.56 vs. 117.88 ± 18.81, p < 0.001; P‐wave amplitude: 0.12 ± 0.04 vs. 0.13 ± 0.04, p = 0.041; interatrial block: 89.6% vs. 10.3%, p < 0.001), congestive heart failure (4.7% vs. 23.2%, p < 0.001), and Killip > 1 (25.3% vs. 55.5%, p < 0.001) showed significant differences between the non‐AF and NOAF groups. P‐wave variables were significantly associated with an increased risk of NOAF in multivariable regression analysis. Conclusions The addition of P‐wave variables to AF risk factors from literature and guidelines significantly improved NOAF risk discrimination. P‐wave variables were strongly associated with NOAF after AMI. Adding these variables enhanced the predictive performance for post‐AMI NOAF.https://doi.org/10.1111/anec.70041acute myocardial infarctionatrial fibrillationinteratrial blockMVP scoreP‐wave amplitudeP‐wave duration |
| spellingShingle | Na Yang Xiaoyan Li Bo Wu Longhao Dai Shaobin Yang Qinning Zhang Shaobin Jia The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction Annals of Noninvasive Electrocardiology acute myocardial infarction atrial fibrillation interatrial block MVP score P‐wave amplitude P‐wave duration |
| title | The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction |
| title_full | The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction |
| title_fullStr | The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction |
| title_full_unstemmed | The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction |
| title_short | The Role of P‐Wave Variables in Enhancing Prediction of New‐Onset Atrial Fibrillation in Patients With Acute Myocardial Infarction |
| title_sort | role of p wave variables in enhancing prediction of new onset atrial fibrillation in patients with acute myocardial infarction |
| topic | acute myocardial infarction atrial fibrillation interatrial block MVP score P‐wave amplitude P‐wave duration |
| url | https://doi.org/10.1111/anec.70041 |
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