Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue

Diffuse reflectance spectrum as a noninvasive method has been widely used to study the optical properties of cutaneous skin tissue. In this work, we optimized an eight-layered optical model of basal cell carcinoma skin tissue to study its optical properties. Based on the model, the diffuse reflectan...

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Main Authors: Miaoqing Nan, Qingli He
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/192495
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author Miaoqing Nan
Qingli He
author_facet Miaoqing Nan
Qingli He
author_sort Miaoqing Nan
collection DOAJ
description Diffuse reflectance spectrum as a noninvasive method has been widely used to study the optical properties of cutaneous skin tissue. In this work, we optimized an eight-layered optical model of basal cell carcinoma skin tissue to study its optical properties. Based on the model, the diffuse reflectance spectra were reconstructed in visible wavelength range by Monte Carlo methods. After different blood contents were added to the optical model, the contribution of blood to diffuese reflectance spectra was investigated theoretically. The ratios of basal cell carcinoma skin and normal skin tissue were also calculated for both experimental result and rebuilt results to testify the theoretical reasonability of the model and methods.
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issn 1537-744X
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spelling doaj-art-7c55c3f55d124a6883b175dad94f69ea2025-02-03T01:22:14ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/192495192495Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin TissueMiaoqing Nan0Qingli He1Department of Physics, Northwest University, Xi’an, Shaanxi 710069, ChinaDepartment of Physics, Northwest University, Xi’an, Shaanxi 710069, ChinaDiffuse reflectance spectrum as a noninvasive method has been widely used to study the optical properties of cutaneous skin tissue. In this work, we optimized an eight-layered optical model of basal cell carcinoma skin tissue to study its optical properties. Based on the model, the diffuse reflectance spectra were reconstructed in visible wavelength range by Monte Carlo methods. After different blood contents were added to the optical model, the contribution of blood to diffuese reflectance spectra was investigated theoretically. The ratios of basal cell carcinoma skin and normal skin tissue were also calculated for both experimental result and rebuilt results to testify the theoretical reasonability of the model and methods.http://dx.doi.org/10.1155/2013/192495
spellingShingle Miaoqing Nan
Qingli He
Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue
The Scientific World Journal
title Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue
title_full Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue
title_fullStr Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue
title_full_unstemmed Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue
title_short Study on the Effect of Blood Content on Diffuse Reflectance Spectra of Basal Cell Carcinoma Skin Tissue
title_sort study on the effect of blood content on diffuse reflectance spectra of basal cell carcinoma skin tissue
url http://dx.doi.org/10.1155/2013/192495
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AT qinglihe studyontheeffectofbloodcontentondiffusereflectancespectraofbasalcellcarcinomaskintissue