NMDA receptors antagonists alleviated the acute phase of traumatic brain injury

NMDA receptors antagonists alleviated the acute phase of traumatic brain injury

Objective(s): Traumatic brain injury (TBI) is a significant cause of mortality and disability worldwide. TBI has been associated with factors such as oxidative stress, neuroinflammation, and apoptosis, which are believed to be mediated by the N-methyl-D-aspartate (NMDA)-type glutamate receptor. Two...

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Bibliographic Details
Main Authors: Mehrdad Hajinejad, Ahmadreza Gharaeian Morshed, Abdolreza Narouiepour, Maryam Izadpanahi, Mohammad Mahdi Taheri, Mohammad hossein Sadeghian, Fatemeh Forouzanfar, Sajad Sahab Negah
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
ketamine
memantine
neuroinflammation
nmda receptor antagonist
oxidative stress
traumatic brain injury
Online Access:https://ijbms.mums.ac.ir/article_25032_c2a5985b963b56490fe0287c38a58a54.pdf
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