Causal associations between inflammatory bowel disease and sepsis: a two-sample Mendelian randomization study

Causal associations between inflammatory bowel disease and sepsis: a two-sample Mendelian randomization study

Abstract Background Recent observational studies have revealed an inconclusive correlation between inflammatory bowel disease (IBD) and sepsis, accompanied by an uncertain understanding of the causal relationship between the two. To investigate the causality between IBD and sepsis, we employed a two...

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Main Authors: Renyang Tong, Ziting Liang, Chengui Zhuo, Xueyang Bai, Ling Dao, Lu Yu, Ling Li, Zhaohui Tong, Youyou Du, Longwei Xu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Medical Genomics
Subjects:
Sepsis
Inflammatory bowel disease
Crohn's disease
Ulcerative colitis
Mendelian randomization
Online Access:https://doi.org/10.1186/s12920-025-02143-2
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https://doi.org/10.1186/s12920-025-02143-2

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