Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference

Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference

Molecular therapy uses nucleic acid-based therapeutics agents and becomes a promising alternative for disease conditions unresponsive to traditional pharmaceutical approaches. Antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs) are two well-known strategies used to modulate gene ex...

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Bibliographic Details
Main Authors: Olga Golounina, Ildar Minniakhmetov, Ramil Salakhov, Rita Khusainova, Ekaterina Zakharova, Igor Bychkov, Natalia Mokrysheva
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Endocrinology
Subjects:
endocrine diseases
molecular therapy
RNA therapeutics
antisense oligonucleotides (ASOs)
small interfering RNA (siRNA)
N-of-1
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1525373/full
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