Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient

Herpes simplex encephalitis is a potentially fatal infection of central nervous system that typically involves frontal and temporal lobes. Occasionally, it presents an extratemporal involvement and in rarer cases, it is limited to the brainstem. We describe a case of an adolescent who presented with...

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Main Authors: Juliana Harumi Arita, Jaime Lin, Mirella Maccarini Peruchi, Marcelo Masruha Rodrigues, Luiz Celso Pereira Vilanova
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2010/606584
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author Juliana Harumi Arita
Jaime Lin
Mirella Maccarini Peruchi
Marcelo Masruha Rodrigues
Luiz Celso Pereira Vilanova
author_facet Juliana Harumi Arita
Jaime Lin
Mirella Maccarini Peruchi
Marcelo Masruha Rodrigues
Luiz Celso Pereira Vilanova
author_sort Juliana Harumi Arita
collection DOAJ
description Herpes simplex encephalitis is a potentially fatal infection of central nervous system that typically involves frontal and temporal lobes. Occasionally, it presents an extratemporal involvement and in rarer cases, it is limited to the brainstem. We describe a case of an adolescent who presented with fever, sore throat, and vertigo. Clinical picture evolved to lethargy, tetraparesis, consciousness impairment, and respiratory failure. MRI showed lesions restricted to the brainstem. PCR of CSF was positive for herpes simplex type 1.
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publishDate 2010-01-01
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spelling doaj-art-7bfb43e93fd54d2a84c1d0ecbee0f1a92025-02-03T05:50:56ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/606584606584Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric PatientJuliana Harumi Arita0Jaime Lin1Mirella Maccarini Peruchi2Marcelo Masruha Rodrigues3Luiz Celso Pereira Vilanova4Division of Child Neurology, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Botucatu 720, 04023-900, São Paulo, BrazilDivision of Child Neurology, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Botucatu 720, 04023-900, São Paulo, BrazilDepartment of Radiology, Faculdade de Medicina, Universidade São Paulo, Av. Dr. Arnaldo 455, 01246903, São Paulo, BrazilDivision of Child Neurology, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Botucatu 720, 04023-900, São Paulo, BrazilDivision of Child Neurology, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, Rua Botucatu 720, 04023-900, São Paulo, BrazilHerpes simplex encephalitis is a potentially fatal infection of central nervous system that typically involves frontal and temporal lobes. Occasionally, it presents an extratemporal involvement and in rarer cases, it is limited to the brainstem. We describe a case of an adolescent who presented with fever, sore throat, and vertigo. Clinical picture evolved to lethargy, tetraparesis, consciousness impairment, and respiratory failure. MRI showed lesions restricted to the brainstem. PCR of CSF was positive for herpes simplex type 1.http://dx.doi.org/10.1155/2010/606584
spellingShingle Juliana Harumi Arita
Jaime Lin
Mirella Maccarini Peruchi
Marcelo Masruha Rodrigues
Luiz Celso Pereira Vilanova
Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient
Case Reports in Medicine
title Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient
title_full Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient
title_fullStr Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient
title_full_unstemmed Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient
title_short Herpes Simplex Type 1 Encephalitis Restricted to the Brainstem in a Pediatric Patient
title_sort herpes simplex type 1 encephalitis restricted to the brainstem in a pediatric patient
url http://dx.doi.org/10.1155/2010/606584
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