Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?

Background. Pervasive refusal syndrome (PRS) is a severe child psychiatric syndrome not yet included in the international classification and mostly affecting girls aged 7-15 years. Hospital admission and severe loss of function extend for many months and years but most recover. Autism has been sugge...

Full description

Saved in:
Bibliographic Details
Main Authors: Håkan Jarbin, Ann-Sofie Saldeen, Carl-Magnus Forslund
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2022/2258180
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832552572688269312
author Håkan Jarbin
Ann-Sofie Saldeen
Carl-Magnus Forslund
author_facet Håkan Jarbin
Ann-Sofie Saldeen
Carl-Magnus Forslund
author_sort Håkan Jarbin
collection DOAJ
description Background. Pervasive refusal syndrome (PRS) is a severe child psychiatric syndrome not yet included in the international classification and mostly affecting girls aged 7-15 years. Hospital admission and severe loss of function extend for many months and years but most recover. Autism has been suggested as a predisposing factor but largely lacks support for typical cases of PRS. Treatment is not evidence-based and described as requiring a lengthy inpatient stay with a very gradual and sensitive rehabilitation program. Case Presentations. Three cases of pervasive refusal syndrome (PRS) in girls aged 9–16 years are presented to report autism as a predisposing factor and to discuss gentle coercion as part of the management strategy to speed up the lengthy recovery. The cases, which met the proposed criteria and typical background characteristics, were noted with the addition of undiagnosed autism in two cases. The duration of inpatient admission was 8–14 months. Disease duration was 15-36 months. An adequate but negative lorazepam trial to rule out catatonia was carried out. Treatment was in one case successfully expedited with gentle coercion within a transparent management plan. Rehabilitation was slower in PRS with comorbid autism; additionally, accommodations to school and living support needed to be put in place. Conclusions. PRS is a useful clinical entity and best perceived as a primitive reaction to overwhelming stress rather than as catatonia. Autism might be another predisposing factor and needs to be assessed. A psychoeducational approach and a clear management plan support rehabilitation. A gentle coercion might hasten recovery.
format Article
id doaj-art-7bd6a97d979d43559075ebe414675118
institution Kabale University
issn 2090-6838
language English
publishDate 2022-01-01
publisher Wiley
record_format Article
series Case Reports in Psychiatry
spelling doaj-art-7bd6a97d979d43559075ebe4146751182025-02-03T05:58:21ZengWileyCase Reports in Psychiatry2090-68382022-01-01202210.1155/2022/2258180Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?Håkan Jarbin0Ann-Sofie Saldeen1Carl-Magnus Forslund2Lund UniversityThe Research UnitLund UniversityBackground. Pervasive refusal syndrome (PRS) is a severe child psychiatric syndrome not yet included in the international classification and mostly affecting girls aged 7-15 years. Hospital admission and severe loss of function extend for many months and years but most recover. Autism has been suggested as a predisposing factor but largely lacks support for typical cases of PRS. Treatment is not evidence-based and described as requiring a lengthy inpatient stay with a very gradual and sensitive rehabilitation program. Case Presentations. Three cases of pervasive refusal syndrome (PRS) in girls aged 9–16 years are presented to report autism as a predisposing factor and to discuss gentle coercion as part of the management strategy to speed up the lengthy recovery. The cases, which met the proposed criteria and typical background characteristics, were noted with the addition of undiagnosed autism in two cases. The duration of inpatient admission was 8–14 months. Disease duration was 15-36 months. An adequate but negative lorazepam trial to rule out catatonia was carried out. Treatment was in one case successfully expedited with gentle coercion within a transparent management plan. Rehabilitation was slower in PRS with comorbid autism; additionally, accommodations to school and living support needed to be put in place. Conclusions. PRS is a useful clinical entity and best perceived as a primitive reaction to overwhelming stress rather than as catatonia. Autism might be another predisposing factor and needs to be assessed. A psychoeducational approach and a clear management plan support rehabilitation. A gentle coercion might hasten recovery.http://dx.doi.org/10.1155/2022/2258180
spellingShingle Håkan Jarbin
Ann-Sofie Saldeen
Carl-Magnus Forslund
Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?
Case Reports in Psychiatry
title Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?
title_full Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?
title_fullStr Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?
title_full_unstemmed Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?
title_short Pervasive Refusal Syndrome: Three Case Reports—Autism as a Predisposing Factor and Gentle Coercion to Shorten Duration of Disorder?
title_sort pervasive refusal syndrome three case reports autism as a predisposing factor and gentle coercion to shorten duration of disorder
url http://dx.doi.org/10.1155/2022/2258180
work_keys_str_mv AT hakanjarbin pervasiverefusalsyndromethreecasereportsautismasapredisposingfactorandgentlecoerciontoshortendurationofdisorder
AT annsofiesaldeen pervasiverefusalsyndromethreecasereportsautismasapredisposingfactorandgentlecoerciontoshortendurationofdisorder
AT carlmagnusforslund pervasiverefusalsyndromethreecasereportsautismasapredisposingfactorandgentlecoerciontoshortendurationofdisorder