Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention
Background. Oral anticoagulants (OAC) effectively reduce the risk for ischemic stroke in patients with atrial fibrillation (AF). We aimed to assess OAC treatment adherence in secondary stroke prevention and to find predictors of adherence using individualized patient data. Methods. This retrospectiv...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Stroke Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2022/5318259 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832558323911622656 |
|---|---|
| author | Riina Vibo Juhan-Mats Kuningas Prinno Tsakuhhin Janika Kõrv |
| author_facet | Riina Vibo Juhan-Mats Kuningas Prinno Tsakuhhin Janika Kõrv |
| author_sort | Riina Vibo |
| collection | DOAJ |
| description | Background. Oral anticoagulants (OAC) effectively reduce the risk for ischemic stroke in patients with atrial fibrillation (AF). We aimed to assess OAC treatment adherence in secondary stroke prevention and to find predictors of adherence using individualized patient data. Methods. This retrospective cohort study included patients with a discharge diagnosis of ischemic stroke and AF from Tartu University Hospital from 2017 to 2018. Data from patient charts and the Electronic Hospital Information, Estonian Electronic Prescription, and Estonian Electronic Health Record systems were registered. Results. Of the 353 patients, 237 (67%) were prescribed OAC treatment at discharge and during the first year after stroke, 202 (85%) of them used OAC treatment. The mean adherence was 81%, while only 68% had good adherence. Reduced non-vitamin K antagonist OAC (NOAC) dose was used in 68 patients (39%), which was justified in 23 (34%). First-ever stroke occurrence was the only significant factor for good treatment adherence in logistic regression analysis. There were 47 patients (23%) with complications among the patients on OAC treatment. Majority of the patients (70%) with hemorrhagic complications and 52% of patients with thromboembolic complications had good treatment adherence Conclusions. Our study showed that OAC treatment adherence following stroke was modest and first-ever stroke was the only predictor of good or full treatment adherence. |
| format | Article |
| id | doaj-art-7bc5aae5486a411ebcb2ea4a64c9ca60 |
| institution | Kabale University |
| issn | 2042-0056 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke Research and Treatment |
| spelling | doaj-art-7bc5aae5486a411ebcb2ea4a64c9ca602025-02-03T01:32:41ZengWileyStroke Research and Treatment2042-00562022-01-01202210.1155/2022/5318259Deceptive Adherence to Anticoagulation in Secondary Stroke PreventionRiina Vibo0Juhan-Mats Kuningas1Prinno Tsakuhhin2Janika Kõrv3Department of Neurology and NeurosurgeryDepartment of Neurology and NeurosurgeryDepartment of Neurology and NeurosurgeryDepartment of Neurology and NeurosurgeryBackground. Oral anticoagulants (OAC) effectively reduce the risk for ischemic stroke in patients with atrial fibrillation (AF). We aimed to assess OAC treatment adherence in secondary stroke prevention and to find predictors of adherence using individualized patient data. Methods. This retrospective cohort study included patients with a discharge diagnosis of ischemic stroke and AF from Tartu University Hospital from 2017 to 2018. Data from patient charts and the Electronic Hospital Information, Estonian Electronic Prescription, and Estonian Electronic Health Record systems were registered. Results. Of the 353 patients, 237 (67%) were prescribed OAC treatment at discharge and during the first year after stroke, 202 (85%) of them used OAC treatment. The mean adherence was 81%, while only 68% had good adherence. Reduced non-vitamin K antagonist OAC (NOAC) dose was used in 68 patients (39%), which was justified in 23 (34%). First-ever stroke occurrence was the only significant factor for good treatment adherence in logistic regression analysis. There were 47 patients (23%) with complications among the patients on OAC treatment. Majority of the patients (70%) with hemorrhagic complications and 52% of patients with thromboembolic complications had good treatment adherence Conclusions. Our study showed that OAC treatment adherence following stroke was modest and first-ever stroke was the only predictor of good or full treatment adherence.http://dx.doi.org/10.1155/2022/5318259 |
| spellingShingle | Riina Vibo Juhan-Mats Kuningas Prinno Tsakuhhin Janika Kõrv Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention Stroke Research and Treatment |
| title | Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention |
| title_full | Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention |
| title_fullStr | Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention |
| title_full_unstemmed | Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention |
| title_short | Deceptive Adherence to Anticoagulation in Secondary Stroke Prevention |
| title_sort | deceptive adherence to anticoagulation in secondary stroke prevention |
| url | http://dx.doi.org/10.1155/2022/5318259 |
| work_keys_str_mv | AT riinavibo deceptiveadherencetoanticoagulationinsecondarystrokeprevention AT juhanmatskuningas deceptiveadherencetoanticoagulationinsecondarystrokeprevention AT prinnotsakuhhin deceptiveadherencetoanticoagulationinsecondarystrokeprevention AT janikakorv deceptiveadherencetoanticoagulationinsecondarystrokeprevention |