Therapeutic approaches for SAPHO syndrome from the perspective of pathogenesis: a review of the literature

Therapeutic approaches for SAPHO syndrome from the perspective of pathogenesis: a review of the literature

Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare autoinflammatory disease characterized by cutaneous manifestations and osteoarticular damage. The pathogenesis of SAPHO syndrome has not yet been elucidated, but studies have shown that the abnormal bone metabolism of...

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Bibliographic Details
Main Authors: Yunuo Wang, Mengjiao Gu, Zixiang Zheng, Haixu Jiang, Luyao Han, Hanjing Huang, Yuanhao Wu, Chen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
SAPHO syndrome
autoimmunity
infection
immune abnormality
bone metabolism
review
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1560398/full
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