394 Inclusion of cytomegalovirus viral Fc gamma receptors in a glycoprotein B protein subunit vaccine improves Fc-mediated effector responses

394 Inclusion of cytomegalovirus viral Fc gamma receptors in a glycoprotein B protein subunit vaccine improves Fc-mediated effector responses

Objectives/Goals: We hypothesized that adding cytomegalovirus (CMV) viral Fc gamma receptors (vFcγRs) to a glycoprotein B (gB) protein subunit vaccine would improve vaccine-elicited Fc mediated effector functions such as antibody dependent cellular phagocytosis (ADCP) and cytotoxicity (ADCC), over g...

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Bibliographic Details
Main Authors: Claire Otero, Mackensie Gross, Savannah Herbek, Megan Connors, Philipp Kolb, Sallie Permar
Format: Article
Language:English
Published: Cambridge University Press 2025-04-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124010136/type/journal_article
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