Anti-Inflammatory Peptide Prevents Aβ<sub>25–35</sub>-Induced Inflammation in Rats via Lipoxygenase Inhibition

Anti-Inflammatory Peptide Prevents Aβ<sub>25–35</sub>-Induced Inflammation in Rats via Lipoxygenase Inhibition

Neuroinflammation, triggered by lipoxygenase (LOX), contributes to Alzheimer’s disease (AD) progression. Overexpression of LOX-5 in patients with AD serum highlights its role. This study assessed the efficacy of the LOX-inhibitor-peptide YWCS in an AD rat model induced by Aβ<sub>25–35</sub&...

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Bibliographic Details
Main Authors: Yudhishthir Yadav, Masroor Anwar, Hanuman Sharma, Suman Jain, Uma Sharma, Partha Haldar, Aparajit B. Dey, Sharmistha Dey
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
lipoxygenase
cognitive behavioral assessment
MRI scan
AD rat model
immunoblot
immunofluorescence
Online Access:https://www.mdpi.com/2073-4409/14/13/957
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