Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province

Background: Substance abuse and its consequences are major health hazards in the world. Opium addiction is a common form of substance abuse in Iran. The present study aims to examine the frequency of clinical and paraclinical symptoms of lead poisoning in opium users in the city of Isfahan. Material...

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Main Authors: Hamid Kalantari, Farzad Gheshlaghi, Marzieh Etezadi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:https://journals.lww.com/10.4103/abr.abr_460_23
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author Hamid Kalantari
Farzad Gheshlaghi
Marzieh Etezadi
author_facet Hamid Kalantari
Farzad Gheshlaghi
Marzieh Etezadi
author_sort Hamid Kalantari
collection DOAJ
description Background: Substance abuse and its consequences are major health hazards in the world. Opium addiction is a common form of substance abuse in Iran. The present study aims to examine the frequency of clinical and paraclinical symptoms of lead poisoning in opium users in the city of Isfahan. Materials and Methods: The current study is a cross-sectional study on patients with oral or inhaled consumption of opium or its derivatives, presenting with one of the clinical or laboratory symptoms of lead poisoning. Information related to the age and sex of the patients, duration and manner of opium consumption, clinical symptoms, and laboratory findings of patients were extracted from their files. Results: Three hundred opium user patients poisoned with lead were evaluated. 96.3% of the patients were men. The average age of the participants was 47.67 ± 11.57 years, and the average duration of opium use was 5.34 ± 6.95 years. The most frequent clinical symptom was abdominal pain (98%), followed by constipation (11.33%), nausea (9%), and vomiting (8.33%). 33.3% of people had an increase in AST, 17.1% of people had an increase in ALT, and 88.3% of people had an increase in ALP. Conclusion: We found that the most frequent clinical symptom was abdominal pain. 33.3% of people had an increase in AST, 17.1% of people had an increase in ALT, 88.3% of people had an increase in ALP and, 4% had an increase in creatine. Further studies are recommended.
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spelling doaj-art-7b55e039a78746b5bf7c328963bbd30a2025-02-06T09:41:42ZengWolters Kluwer Medknow PublicationsAdvanced Biomedical Research2277-91752025-01-011417710.4103/abr.abr_460_23Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan ProvinceHamid KalantariFarzad GheshlaghiMarzieh EtezadiBackground: Substance abuse and its consequences are major health hazards in the world. Opium addiction is a common form of substance abuse in Iran. The present study aims to examine the frequency of clinical and paraclinical symptoms of lead poisoning in opium users in the city of Isfahan. Materials and Methods: The current study is a cross-sectional study on patients with oral or inhaled consumption of opium or its derivatives, presenting with one of the clinical or laboratory symptoms of lead poisoning. Information related to the age and sex of the patients, duration and manner of opium consumption, clinical symptoms, and laboratory findings of patients were extracted from their files. Results: Three hundred opium user patients poisoned with lead were evaluated. 96.3% of the patients were men. The average age of the participants was 47.67 ± 11.57 years, and the average duration of opium use was 5.34 ± 6.95 years. The most frequent clinical symptom was abdominal pain (98%), followed by constipation (11.33%), nausea (9%), and vomiting (8.33%). 33.3% of people had an increase in AST, 17.1% of people had an increase in ALT, and 88.3% of people had an increase in ALP. Conclusion: We found that the most frequent clinical symptom was abdominal pain. 33.3% of people had an increase in AST, 17.1% of people had an increase in ALT, 88.3% of people had an increase in ALP and, 4% had an increase in creatine. Further studies are recommended.https://journals.lww.com/10.4103/abr.abr_460_23lead poisoningopiumsigns and symptoms
spellingShingle Hamid Kalantari
Farzad Gheshlaghi
Marzieh Etezadi
Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province
Advanced Biomedical Research
lead poisoning
opium
signs and symptoms
title Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province
title_full Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province
title_fullStr Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province
title_full_unstemmed Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province
title_short Examining the Frequency of Clinical and Paraclinical Symptoms in Opium Addicts Hospitalized Due to Lead Poisoning in Isfahan Province
title_sort examining the frequency of clinical and paraclinical symptoms in opium addicts hospitalized due to lead poisoning in isfahan province
topic lead poisoning
opium
signs and symptoms
url https://journals.lww.com/10.4103/abr.abr_460_23
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AT marziehetezadi examiningthefrequencyofclinicalandparaclinicalsymptomsinopiumaddictshospitalizedduetoleadpoisoninginisfahanprovince