STModule: identifying tissue modules to uncover spatial components and characteristics of transcriptomic landscapes

Abstract Here we present STModule, a Bayesian method developed to identify tissue modules from spatially resolved transcriptomics that reveal spatial components and essential characteristics of tissues. STModule uncovers diverse expression signals in transcriptomic landscapes such as cancer, intraep...

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Bibliographic Details
Main Authors: Ran Wang, Yan Qian, Xiaojing Guo, Fangda Song, Zhiqiang Xiong, Shirong Cai, Xiuwu Bian, Man Hon Wong, Qin Cao, Lixin Cheng, Gang Lu, Kwong Sak Leung
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Genome Medicine
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Online Access:https://doi.org/10.1186/s13073-025-01441-9
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