Congo red fluorescence enhances digital pathology workflow in cardiac amyloidosis

Congo red fluorescence enhances digital pathology workflow in cardiac amyloidosis

Abstract Despite advances in non-invasive methods, endomyocardial biopsy (EMB) remains essential for definitive diagnosis of amyloidosis in many cases. Traditionally, Congo red birefringence (CRB) has been crucial for identifying amyloid deposits but is challenging to capture digitally. Emerging flu...

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Bibliographic Details
Main Authors: Giorgio Cazzaniga, Monica De Gaspari, Vincenzo L’Imperio, Carlo Beretta, Angela Greco, Stefania Rizzo, Cristina Basso, Fabio Pagni
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Digital pathology
Cardiac amyloidosis
Artificial intelligence
Congo red
Cardiovascular pathology
Online Access:https://doi.org/10.1038/s41598-025-07157-5
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