Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis
Purpose. To study epidemiology, clinical findings and visual prognosis of patients with Fuchs’ Heterochromic Iridocyclitis (FHI). Methods. A retrospective analysis was performed on 158 patients with FHI. Thirty-five patients were observed only once; the remaining 123 had a mean follow-up of 30.7 mon...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2016/1458624 |
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| author | Massimo Accorinti Giovanni Spinucci Maria Pia Pirraglia Simone Bruschi Francesca Romana Pesci Ludovico Iannetti |
| author_facet | Massimo Accorinti Giovanni Spinucci Maria Pia Pirraglia Simone Bruschi Francesca Romana Pesci Ludovico Iannetti |
| author_sort | Massimo Accorinti |
| collection | DOAJ |
| description | Purpose. To study epidemiology, clinical findings and visual prognosis of patients with Fuchs’ Heterochromic Iridocyclitis (FHI). Methods. A retrospective analysis was performed on 158 patients with FHI. Thirty-five patients were observed only once; the remaining 123 had a mean follow-up of 30.7 months (50 of them had a mean follow-up of 63.5 months) and in those we assessed complications, medical and surgical treatment, and long-term visual prognosis. Results. Average age at uveitis diagnosis was 27.2 years and 18.3% of patients were children. Blurred vision (54.5%) and floaters (40.5%) were the most frequent presenting symptoms. Small to medium-sized keratic precipitates (95.6%), iris atrophy (86.8%), and vitreous opacities (91.2%) were the most common signs; the prevalence of cataract and IOP increase was 63.5% and 20.1%, respectively, and their incidence was 0.1 and 0.06 eye/year. Significant risk factor for visual loss was IOP increase at presentation (p=0.02). At final examination 98% of the eye had a visual acuity ≥ 0.6, and topical (p<0.001) and systemic (p<0.001) corticosteroids therapy were used less frequently than before referral. Conclusions. FHI has a good visual prognosis, despite the significant incidence of cataract and glaucoma. A correct and prompt diagnosis might avoid unnecessary therapies and provide excellent visual outcomes. |
| format | Article |
| id | doaj-art-7b0b4b4cb5f4439f81a1602d95968298 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-7b0b4b4cb5f4439f81a1602d959682982025-02-03T05:43:39ZengWileyJournal of Ophthalmology2090-004X2090-00582016-01-01201610.1155/2016/14586241458624Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and PrognosisMassimo Accorinti0Giovanni Spinucci1Maria Pia Pirraglia2Simone Bruschi3Francesca Romana Pesci4Ludovico Iannetti5Department of Ophthalmology, Sapienza University of Rome, Rome, ItalyDepartment of Ophthalmology, Sapienza University of Rome, Rome, ItalyDepartment of Ophthalmology, Sapienza University of Rome, Rome, ItalyDepartment of Ophthalmology, Sapienza University of Rome, Rome, ItalyDepartment of Ophthalmology, Sapienza University of Rome, Rome, ItalyDepartment of Ophthalmology, Sapienza University of Rome, Rome, ItalyPurpose. To study epidemiology, clinical findings and visual prognosis of patients with Fuchs’ Heterochromic Iridocyclitis (FHI). Methods. A retrospective analysis was performed on 158 patients with FHI. Thirty-five patients were observed only once; the remaining 123 had a mean follow-up of 30.7 months (50 of them had a mean follow-up of 63.5 months) and in those we assessed complications, medical and surgical treatment, and long-term visual prognosis. Results. Average age at uveitis diagnosis was 27.2 years and 18.3% of patients were children. Blurred vision (54.5%) and floaters (40.5%) were the most frequent presenting symptoms. Small to medium-sized keratic precipitates (95.6%), iris atrophy (86.8%), and vitreous opacities (91.2%) were the most common signs; the prevalence of cataract and IOP increase was 63.5% and 20.1%, respectively, and their incidence was 0.1 and 0.06 eye/year. Significant risk factor for visual loss was IOP increase at presentation (p=0.02). At final examination 98% of the eye had a visual acuity ≥ 0.6, and topical (p<0.001) and systemic (p<0.001) corticosteroids therapy were used less frequently than before referral. Conclusions. FHI has a good visual prognosis, despite the significant incidence of cataract and glaucoma. A correct and prompt diagnosis might avoid unnecessary therapies and provide excellent visual outcomes.http://dx.doi.org/10.1155/2016/1458624 |
| spellingShingle | Massimo Accorinti Giovanni Spinucci Maria Pia Pirraglia Simone Bruschi Francesca Romana Pesci Ludovico Iannetti Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis Journal of Ophthalmology |
| title | Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis |
| title_full | Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis |
| title_fullStr | Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis |
| title_full_unstemmed | Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis |
| title_short | Fuchs’ Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis |
| title_sort | fuchs heterochromic iridocyclitis in an italian tertiary referral centre epidemiology clinical features and prognosis |
| url | http://dx.doi.org/10.1155/2016/1458624 |
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