Absence of astrocytic ceruloplasmin reverses the senescence process with aging of learning and memory abilities

Absence of astrocytic ceruloplasmin reverses the senescence process with aging of learning and memory abilities

Ceruloplasmin (CP) is a multi-copper ferroxidase mainly synthesized by liver, secreted into the peripheral blood, playing a critical role in regulating the iron homeostasis. In the central nervous system (CNS), the CP expressed by astrocytes plays an important role in the transportation of iron from...

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Bibliographic Details
Main Authors: Zhong-Da Li, Shaomeng Kang, Haiyan Li, Peng Yu, Ruikun Xie, Chenchen Li, Qi Jing, Zhengzheng Gong, Li Li, Zhengning Li, Mengyu Geng, Zihan Zhang, Yang Li, Yan-Zhong Chang
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Redox Biology
Subjects:
Ceruloplasmin
Astrocytes
Senescence
Recognition
Brain iron metabolism
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725001247
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