Multidisciplinary Management of Soft Tissue Sarcoma
Soft tissue sarcoma is a rare malignancy, with approximately 11,000 cases per year encountered in the United States. It is primarily encountered in adults but can affect patients of any age. There are many histologic subtypes and the malignancy can be low or high grade. Appropriate staging work up i...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2013/852462 |
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| author | Lukas M. Nystrom Nickolas B. Reimer John D. Reith Long Dang Robert A. Zlotecki Mark T. Scarborough C. Parker Gibbs |
| author_facet | Lukas M. Nystrom Nickolas B. Reimer John D. Reith Long Dang Robert A. Zlotecki Mark T. Scarborough C. Parker Gibbs |
| author_sort | Lukas M. Nystrom |
| collection | DOAJ |
| description | Soft tissue sarcoma is a rare malignancy, with approximately 11,000 cases per year encountered in the United States. It is primarily encountered in adults but can affect patients of any age. There are many histologic subtypes and the malignancy can be low or high grade. Appropriate staging work up includes a physical exam, advanced imaging, and a carefully planned biopsy. This information is then used to guide the discussion of definitive treatment of the tumor which typically involves surgical resection with a negative margin in addition to neoadjuvant or adjuvant external beam radiation. Advances in imaging and radiation therapy have made limb salvage surgery the standard of care, with local control rates greater than 90% in most modern series. Currently, the role of chemotherapy is not well defined and this treatment is typically reserved for patients with metastatic or recurrent disease and for certain histologic subtypes. The goal of this paper is to review the current state of the art in multidisciplinary management of soft tissue sarcoma. |
| format | Article |
| id | doaj-art-7aee29dd5c5b4922940fd338f1414835 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-7aee29dd5c5b4922940fd338f14148352025-02-03T01:31:35ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/852462852462Multidisciplinary Management of Soft Tissue SarcomaLukas M. Nystrom0Nickolas B. Reimer1John D. Reith2Long Dang3Robert A. Zlotecki4Mark T. Scarborough5C. Parker Gibbs6Orthopaedic & Sports Medicine Institute, University of Florida, 3450 Hull Road, Gainesville, FL 32605, USAOrthopaedic & Sports Medicine Institute, University of Florida, 3450 Hull Road, Gainesville, FL 32605, USADepartment of Pathology, Immunology and Laboratory Medicine, University of Florida, 1600 SW Archer Road, Gainesville, FL 32608, USADepartment of Medicine, Division of Hematology & Oncology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32608, USADepartment of Radiation Oncology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32608, USAOrthopaedic & Sports Medicine Institute, University of Florida, 3450 Hull Road, Gainesville, FL 32605, USAOrthopaedic & Sports Medicine Institute, University of Florida, 3450 Hull Road, Gainesville, FL 32605, USASoft tissue sarcoma is a rare malignancy, with approximately 11,000 cases per year encountered in the United States. It is primarily encountered in adults but can affect patients of any age. There are many histologic subtypes and the malignancy can be low or high grade. Appropriate staging work up includes a physical exam, advanced imaging, and a carefully planned biopsy. This information is then used to guide the discussion of definitive treatment of the tumor which typically involves surgical resection with a negative margin in addition to neoadjuvant or adjuvant external beam radiation. Advances in imaging and radiation therapy have made limb salvage surgery the standard of care, with local control rates greater than 90% in most modern series. Currently, the role of chemotherapy is not well defined and this treatment is typically reserved for patients with metastatic or recurrent disease and for certain histologic subtypes. The goal of this paper is to review the current state of the art in multidisciplinary management of soft tissue sarcoma.http://dx.doi.org/10.1155/2013/852462 |
| spellingShingle | Lukas M. Nystrom Nickolas B. Reimer John D. Reith Long Dang Robert A. Zlotecki Mark T. Scarborough C. Parker Gibbs Multidisciplinary Management of Soft Tissue Sarcoma The Scientific World Journal |
| title | Multidisciplinary Management of Soft Tissue Sarcoma |
| title_full | Multidisciplinary Management of Soft Tissue Sarcoma |
| title_fullStr | Multidisciplinary Management of Soft Tissue Sarcoma |
| title_full_unstemmed | Multidisciplinary Management of Soft Tissue Sarcoma |
| title_short | Multidisciplinary Management of Soft Tissue Sarcoma |
| title_sort | multidisciplinary management of soft tissue sarcoma |
| url | http://dx.doi.org/10.1155/2013/852462 |
| work_keys_str_mv | AT lukasmnystrom multidisciplinarymanagementofsofttissuesarcoma AT nickolasbreimer multidisciplinarymanagementofsofttissuesarcoma AT johndreith multidisciplinarymanagementofsofttissuesarcoma AT longdang multidisciplinarymanagementofsofttissuesarcoma AT robertazlotecki multidisciplinarymanagementofsofttissuesarcoma AT marktscarborough multidisciplinarymanagementofsofttissuesarcoma AT cparkergibbs multidisciplinarymanagementofsofttissuesarcoma |