Piezo1 deletion enhances cross-priming of CD8+ T cells by tumor-infiltrating CD11b+ dendritic cells

Piezo1 deletion enhances cross-priming of CD8+ T cells by tumor-infiltrating CD11b+ dendritic cells

Background Tumor-associated myeloid cells (TAMCs) are an abundant, phenotypically plastic cell population that is critical for initiating a robust antitumor response. To properly combat cancer cells, TAMCs must sense and transduce both soluble and vital biophysical cues imparted by the dense extrace...

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Bibliographic Details
Main Authors: Tyler E Miller, Phuong Nguyen, Suzanne L Tomchuck, Jay T Myers, Saada Eid, Muta Abiff, Melissa Bonner, Alex Yee-Chen Huang, David Askew, Vrishabhadev Sathish Kumar, Justin W A Garyu
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/13/6/e011815.full
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