Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review

Poly(lactic-co-glycolic acid) or PLGA is a biodegradable polymer used in a wide range of medical applications. Specifically PLGA materials are also developed for the dental field in the form of scaffolds, films, membranes, microparticles, or nanoparticles. PLGA membranes have been studied with promi...

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Main Authors: Maria Justina Roxana Virlan, Daniela Miricescu, Alexandra Totan, Maria Greabu, Cristiana Tanase, Cristina M. Sabliov, Constantin Caruntu, Bogdan Calenic
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2015/525832
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author Maria Justina Roxana Virlan
Daniela Miricescu
Alexandra Totan
Maria Greabu
Cristiana Tanase
Cristina M. Sabliov
Constantin Caruntu
Bogdan Calenic
author_facet Maria Justina Roxana Virlan
Daniela Miricescu
Alexandra Totan
Maria Greabu
Cristiana Tanase
Cristina M. Sabliov
Constantin Caruntu
Bogdan Calenic
author_sort Maria Justina Roxana Virlan
collection DOAJ
description Poly(lactic-co-glycolic acid) or PLGA is a biodegradable polymer used in a wide range of medical applications. Specifically PLGA materials are also developed for the dental field in the form of scaffolds, films, membranes, microparticles, or nanoparticles. PLGA membranes have been studied with promising results, either alone or combined with other materials in bone healing procedures. PLGA scaffolds have been used to regenerate damaged tissues together with stem cell-based therapy. There is solid evidence that the development of PLGA microparticles and nanoparticles may be beneficial to a wide range of dental fields such as endodontic therapy, dental caries, dental surgery, dental implants, or periodontology. The aim of the current paper was to review the recent advances in PLGA materials and their potential uses in the dental field.
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spelling doaj-art-7ad6c3f10dd442dfb165e03a0723136c2025-02-03T05:51:54ZengWileyJournal of Chemistry2090-90632090-90712015-01-01201510.1155/2015/525832525832Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive ReviewMaria Justina Roxana Virlan0Daniela Miricescu1Alexandra Totan2Maria Greabu3Cristiana Tanase4Cristina M. Sabliov5Constantin Caruntu6Bogdan Calenic7Department of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, RomaniaDepartment of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, RomaniaDepartment of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, RomaniaDepartment of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, RomaniaBiochemistry-Proteomics Department, “Victor Babes” National Institute of Pathology, No. 99 101, Splaiul Independentei, Sector 5, 050096 Bucharest, RomaniaAgricultural and Biological Engineering Department, Louisiana State University and LSU Ag Center, 149 EB Doran Building, Baton Rouge, LA 70803, USADepartment of Physiology, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaDepartment of Biochemistry, Faculty of Dentistry, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, RomaniaPoly(lactic-co-glycolic acid) or PLGA is a biodegradable polymer used in a wide range of medical applications. Specifically PLGA materials are also developed for the dental field in the form of scaffolds, films, membranes, microparticles, or nanoparticles. PLGA membranes have been studied with promising results, either alone or combined with other materials in bone healing procedures. PLGA scaffolds have been used to regenerate damaged tissues together with stem cell-based therapy. There is solid evidence that the development of PLGA microparticles and nanoparticles may be beneficial to a wide range of dental fields such as endodontic therapy, dental caries, dental surgery, dental implants, or periodontology. The aim of the current paper was to review the recent advances in PLGA materials and their potential uses in the dental field.http://dx.doi.org/10.1155/2015/525832
spellingShingle Maria Justina Roxana Virlan
Daniela Miricescu
Alexandra Totan
Maria Greabu
Cristiana Tanase
Cristina M. Sabliov
Constantin Caruntu
Bogdan Calenic
Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
Journal of Chemistry
title Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
title_full Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
title_fullStr Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
title_full_unstemmed Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
title_short Current Uses of Poly(lactic-co-glycolic acid) in the Dental Field: A Comprehensive Review
title_sort current uses of poly lactic co glycolic acid in the dental field a comprehensive review
url http://dx.doi.org/10.1155/2015/525832
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