Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats

The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive...

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Main Authors: Alexander Thomas Andreas Weiss, Werner Hecht, Manfred Reinacher
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.4061/2010/953272
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author Alexander Thomas Andreas Weiss
Werner Hecht
Manfred Reinacher
author_facet Alexander Thomas Andreas Weiss
Werner Hecht
Manfred Reinacher
author_sort Alexander Thomas Andreas Weiss
collection DOAJ
description The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor 𝛾 locus are also described.
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series Veterinary Medicine International
spelling doaj-art-7aaf0ce928ab4fb8a5c6c56ddda705082025-02-03T07:25:31ZengWileyVeterinary Medicine International2042-00482010-01-01201010.4061/2010/953272953272Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of CatsAlexander Thomas Andreas Weiss0Werner Hecht1Manfred Reinacher2Institute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, GermanyInstitute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, GermanyInstitute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, GermanyThe variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor 𝛾 locus are also described.http://dx.doi.org/10.4061/2010/953272
spellingShingle Alexander Thomas Andreas Weiss
Werner Hecht
Manfred Reinacher
Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
Veterinary Medicine International
title Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
title_full Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
title_fullStr Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
title_full_unstemmed Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
title_short Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
title_sort feline t cell receptor 𝛾 v and j region sequences retrieved from the trace archive and from transcriptome analysis of cats
url http://dx.doi.org/10.4061/2010/953272
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