Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive...
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Format: | Article |
Language: | English |
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Wiley
2010-01-01
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Series: | Veterinary Medicine International |
Online Access: | http://dx.doi.org/10.4061/2010/953272 |
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author | Alexander Thomas Andreas Weiss Werner Hecht Manfred Reinacher |
author_facet | Alexander Thomas Andreas Weiss Werner Hecht Manfred Reinacher |
author_sort | Alexander Thomas Andreas Weiss |
collection | DOAJ |
description | The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor 𝛾 locus are also described. |
format | Article |
id | doaj-art-7aaf0ce928ab4fb8a5c6c56ddda70508 |
institution | Kabale University |
issn | 2042-0048 |
language | English |
publishDate | 2010-01-01 |
publisher | Wiley |
record_format | Article |
series | Veterinary Medicine International |
spelling | doaj-art-7aaf0ce928ab4fb8a5c6c56ddda705082025-02-03T07:25:31ZengWileyVeterinary Medicine International2042-00482010-01-01201010.4061/2010/953272953272Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of CatsAlexander Thomas Andreas Weiss0Werner Hecht1Manfred Reinacher2Institute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, GermanyInstitute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, GermanyInstitute of Veterinary Pathology, University of Giessen, Frankfurter Strasse 96, 35392 Giessen, GermanyThe variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. Here we describe additional variants of V- and J-region genes of the feline T-cell receptor 𝛾 (TRG) as well as the corresponding RSSs retrieved from Trace Archive of feline genomic sequences. Additionally, an unusually recombined TRGV-domain containing a partial inverted repeat of the included J-region and a short interspersed element of the CAN-SINE family located within the feline T-cell receptor 𝛾 locus are also described.http://dx.doi.org/10.4061/2010/953272 |
spellingShingle | Alexander Thomas Andreas Weiss Werner Hecht Manfred Reinacher Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats Veterinary Medicine International |
title | Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_full | Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_fullStr | Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_full_unstemmed | Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_short | Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats |
title_sort | feline t cell receptor 𝛾 v and j region sequences retrieved from the trace archive and from transcriptome analysis of cats |
url | http://dx.doi.org/10.4061/2010/953272 |
work_keys_str_mv | AT alexanderthomasandreasweiss felinetcellreceptorγvandjregionsequencesretrievedfromthetracearchiveandfromtranscriptomeanalysisofcats AT wernerhecht felinetcellreceptorγvandjregionsequencesretrievedfromthetracearchiveandfromtranscriptomeanalysisofcats AT manfredreinacher felinetcellreceptorγvandjregionsequencesretrievedfromthetracearchiveandfromtranscriptomeanalysisofcats |